Biomedical Engineering Reference
In-Depth Information
FIGURE 9.10: (See color insert.) 3D cell migration as a function of fiber
rigidity perimete F and pore size. Contour plots of cell migratory parameters
for (A) standard conditions (see Figure 9.1) that further include the absence of
proteolytic activity and a stiff nucleus ( surface
;N
= 8.5), (B) cells as in (A) but
with an elastic nucleus ( surface
;N = 0.5), and (C) cells as in (A) but expressing
matrix degrading enzymes, regulated by Equation (9.6). Each value is given
as the mean over 50 randomly chosen individuals (see Section 9.2.1).
 
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