Biomedical Engineering Reference
In-Depth Information
FIGURE 6.13: (See color insert.) Inhibition of active cytoskeletal reorgani-
zation,
surface
;C
= 50. (A) Three-dimensional view of cell position (red dot
represents the VEGF source), (B) and (C) contour plots showing intracellular
calcium concentration during cell motion in, respectively, z = 1 m plane and
y = 50 m plane. For (A), (B), and (C) representative images taken, as usu-
ally, at 45 min intervals until t = 6. (D) Evolution in time of cell directional
velocity v
x
. (E) Ca
2+
concentration profiles at the end of migration, t = 6
h, along cell x-cross-section of the z = 1 m plane from the trailing edge to
the leading edge. Mean over 10 simulations; the error bars represent standard
deviation.
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