Biomedical Engineering Reference
In-Depth Information
FIGURE 6.12: (See color insert.) Cell migration with interference in the
buffering process. (A) Three-dimensional view of cell position at t = 6 h
in the case of buffer clusterization, and relative contour plots of the final
intracellular calcium concentration in (B) z = 1 m plane and (C) y = 50
m plane. In (A) red dot represents the VEGF source. (D) Evolution in time
of cell directional velocity v
x
in both cases. (E) Ca
2+
concentration profiles
at the end of migration, t = 5 h in the absence of buffers and t = 6 h in the
case of clusterized buers, along cell x-cross-section of the z = 1 m plane
from the trailing edge to the leading edge of the polarized cell. Mean over 10
simulations; the error bars represent standard deviation.
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