Diversity of Human Clock Genotypes and Consequences - Progress in Molecular Biology and Translational Science - page 78

67. Chu LW, Zhu Y, Yu K, et al. Variants in circadian genes and prostate cancer
risk: a population-based study in China. Prostate Cancer Prostatic Dis . 2008;11

(4):342-348.
68. Zhu Y, Stevens RG, Leaderer D, et al. Non-synonymous polymorphisms in the cir-
cadian gene NPAS2 and breast cancer risk. Breast Cancer Res Treat . 2008;107

(3):421-425.
69. Chu LW, Zhu Y, Yu K, et al. Correlation between circadian gene variants and serum
levels of sex steroids and insulin-like growth factor-I. Cancer Epidemiol Biomarkers Prev .
2008;17(11):3268-3273.
70. Carpen JD, von Schantz M, Smits M, Skene DJ, Archer SN. A silent polymorphism in
the PER1 gene associates with extreme diurnal preference in humans. J Hum Genet .

2006;51(12):1122-1125.
71. Dong L, Bilbao A, Laucht M, et al. Effects of the circadian rhythm gene period 1 (per1)
on psychosocial

Am J Psychiatry . 2011;168

stress-induced alcohol drinking.

(10):1090-1098.
72. Medicine AAoS . International Classification of Sleep Disorders, 2nd ed.: Diagnostic and
Coding Manual. Westchester, IL: American Academy of Sleep Medicine; 2005.
73. Jones CR, Campbell SS, Zone SE, et al. Familial advanced sleep-phase syndrome:
a short-period circadian rhythm variant in humans. Nat Med . 1999;5(9):1062-1065.
74. Campbell SS, Gillin JC, Kripke DF, Erikson P, Clopton P. Gender differences in the
circadian temperature rhythms of healthy elderly subjects: relationships to sleep quality.
Sleep . 1989;12(6):529-536.
75. Haimov I, Lavie P. Circadian characteristics of sleep propensity function in healthy
elderly: a comparison with young adults. Sleep . 1997;20(4):294-300.
76. Toh KL, Jones CR, He Y, et al. An hPer2 phosphorylation site mutation in familial
advanced sleep phase syndrome. Science . 2001;291(5506):1040-1043.
77. Xu Y, Toh KL, Jones CR, Shin J-Y, Fu Y-H, Ptacek LJ. Modeling of a human
circadian mutation yields insights into clock regulation by PER2. Cell .

2007;128:59-70.
78. Carpen JD, Archer SN, Skene DJ, Smits M, von Schantz M. A single-nucleotide poly-
morphism in the 5 0 -untranslated region of the hPER2 gene is associated with diurnal
preference. J Sleep Res . 2005;14(3):293-297.
79. Lee HJ, Kim L, Kang SG, et al. PER2 variation is associated with diurnal preference in a
Korean young population. Behav Genet . 2011;41(2):273-277.
80. Lavebratt C, Sjoholm LK, Partonen T, Schalling M, Forsell Y. PER2 variantion is asso-
ciated with depression vulnerability. Am J Med Genet B Neuropsychiatr Genet . 2010;153B
(2):570-581.
81. Forbes EE, Dahl RE, Almeida JR, et al. PER2 rs2304672 polymorphism moderates
circadian-relevant reward circuitry activity in adolescents. Biol Psychiatry . 2012;71
(5):451-457.
82. Abarca C, Albrecht U, Spanagel R. Cocaine sensitization and reward are under the
influence of circadian genes and rhythm.

Proc Natl Acad Sci USA . 2002;99

(13):9026-9030.
83. Garaulet M, Corbalan-Tutau MD, Madrid JA, et al. PERIOD2 variants are associated
with abdominal obesity, psycho-behavioral factors, and attrition in the dietary treat-
ment of obesity. J Am Diet Assoc . 2010;110(6):917-921.
84. Garcia-Rios A, Perez-Martinez P, Delgado-Lista J, et al. A Period 2 genetic variant
interacts with plasma SFA to modify plasma lipid concentrations in adults with meta-
bolic syndrome. J Nutr . 2012;142(7):1213-1218.
85. Spanagel R, Pendyala G, Abarca C, et al. The clock gene Per2 influences the gluta-
matergic system and modulates alcohol consumption. Nat Med . 2005;11:35-42.