Diversity of Human Clock Genotypes and Consequences - Progress in Molecular Biology and Translational Science - page 75

10. Gotter AL. A Timeless debate: resolving TIM's noncircadian roles with possible clock
function. Neuroreport . 2006;17(12):1229-1233.
11. Akashi M, Tsuchiya Y, Yoshino T, Nishida E. Control of intracellular dynamics of
mammalian period proteins by casein kinase I epsilon (CKIepsilon) and CKIdelta in
cultured cells. Mol Cell Biol . 2002;22(6):1693-1703.
12. Lowrey PL, Shimomura K, Antoch MP, et al. Positional syntenic cloning and func-
tional characterization of the mammalian circadian mutation tau. Science . 2000;288
(5465):483-492.
13. Meng QJ, Logunova L, Maywood ES, et al. Setting clock speed in mammals: the CK1
epsilon tau mutation in mice accelerates circadian pacemakers by selectively
destabilizing PERIOD proteins. Neuron . 2008;58(1):78-88.
14. Xu Y, Padiath QS, Shapiro RE, et al. Functional consequences of a CKIdelta mutation
causing familial advanced sleep phase syndrome. Nature . 2005;434(7033):640-644.
15. Eide EJ, Woolf MF, Kang H, et al. Control of mammalian circadian rhythm by
CK1epsilon-regulated proteasome-mediated PER2 degradation. Mol Cell Biol .
2005;25:2795-2807.
16. Shirogane T, Jin J, Ang XL, Harper JW. SCF b TRCP controls clock-dependent tran-
scription via casein kinase 1-dependent degradation of the mammalian Period-1
(Per1) protein. J Biol Chem . 2005;280:26863-26872.
17. Reischl S, Vanselow K, Westermark PO, et al. Beta-TrCP1-mediated degradation of
PERIOD2 is essential for circadian dynamics. J Biol Rhythms . 2007;22(5):375-386.
18. Busino L, Bassermann F, Maiolica A, et al. SCFFbxl3 controls the oscillation of the
circadian clock by directing the degradation of cryptochrome proteins. Science .

2007;316(5826):900-904.
19. Godinho SI, Maywood ES, Shaw L, et al. The after-hours mutant reveals a role for
Fbxl3 in determining mammalian circadian period. Science . 2007;316(5826):897-900.
20. Siepka SM, Yoo SH, Park J, et al. Circadian mutant overtime reveals F-box protein
FBXL3 regulation of cryptochrome and period gene expression. Cell . 2007;129
(5):1011-1023.
21. Woon PY, Kaisaki PJ, Braganca J, et al. Aryl hydrocarbon receptor nuclear
translocator-like (BMAL1) is associated with susceptibility to hypertension and type
2 diabetes. Proc Natl Acad Sci USA . 2007;104(36):14412-14417.
22. Marcheva B, Ramsey KM, Buhr ED, et al. Disruption of the clock components
CLOCK and BMAL1 leads to hypoinsulinaemia and diabetes. Nature . 2010;466
(7306):627-631.
23. Zhu Y, Stevens RG, Hoffman AE, et al. Testing the circadian gene hypothesis in pros-
tate cancer: a population-based case-control study. Cancer Res . 2009;69

(24):9315-9322.
24. Partonen T, Treutlein J, Alpman A, et al. Three circadian clock genes Per2, Arntl, and
Npas2 contribute to winter depression. Ann Med . 2007;39(3):229-238.
25. Kovanen L, Saarikoski ST, Aromaa A, Lonnqvist J, Partonen T. ARNTL (BMAL1)
and NPAS2 gene variants contribute to fertility and seasonality. PLoS One . 2010;5
(4):e10007.
26. Alvarez JD, Hansen A, Ord T, et al. The circadian clock protein BMAL1 is necessary
for fertility and proper testosterone production in mice. J Biol Rhythms . 2008;23

(1):26-36.
27. Boden MJ, Varcoe TJ, Voultsios A, Kennaway DJ. Reproductive biology of female
Bmal1 null mice. Reproduction . 2010;139(6):1077-1090.
28. Kovanen L, Saarikoski ST, Haukka J, et al. Circadian clock gene polymorphisms in
alcohol use disorders and alcohol consumption. Alcohol Alcohol . 2010;45(4):303-311.
29. Katzenberg D, Young T, Finn L, et al. A CLOCK polymorphism associated with
human diurnal preference. Sleep . 1998;21(6):569-576.