Health Consequences of Circadian Disruption in Humans and Animal Models - Progress in Molecular Biology and Translational Science - page 314

221. Zhao Y, Zhang Y, Zhou M, et al. Loss of mPer2 increases plasma insulin levels by
enhanced glucose-stimulated insulin secretion and impaired insulin clearance in mice.
FEBS Lett . 2012;586:1306-1311.
222. Yang S, Liu A, Weidenhammer A, et al. The role of mPer2 clock gene in glucocorticoid
and feeding rhythms. Endocrinology . 2009;150:2153-2160.
223. Lamia KA, Papp SJ, Yu RT, et al. Cryptochromes mediate rhythmic repression of the
glucocorticoid receptor. Nature . 2011;480:552-556.
224. Doi M, Takahashi Y, Komatsu R, et al. Salt-sensitive hypertension in circadian clock-
deficient Cry-null mice involves dysregulated adrenal Hsd3b6. Nat Med .

2010;16:67-74.
225. Okano S, Hayasaka K, Igarashi M, et al. Non-obese early onset diabetes mellitus in
mutant cryptochrome1 transgenic mice. Eur J Clin Invest . 2010;40:1011-1017.
226. Okano S, Akashi M, Hayasaka K, Nakajima O. Unusual circadian locomotor activity
and

Neurosci Lett .

pathophysiology in mutant CRY1 transgenic mice.

2009;451:246-251.
227. Bugge A, Feng D, Everett LJ, et al. Rev-erbalpha and Rev-erbbeta coordinately pro-
tect the circadian clock and normal metabolic function. Genes Dev . 2012;26:657-667.
228. Cho H, Zhao X, Hatori M, et al. Regulation of circadian behaviour and metabolism by
REV-ERB-alpha and REV-ERB-beta. Nature . 2012;485:123-127.
229. Woon PY, Kaisaki PJ, Braganca J, et al. Aryl hydrocarbon receptor nuclear
translocator-like (BMAL1) is associated with susceptibility to hypertension and type
2 diabetes. Proc Natl Acad Sci USA . 2007;104:14412-14417.
230. Garaulet M, Esteban Tardido A, Lee YC, et al. SIRT1 and CLOCK 3111T > C com-
bined genotype is associated with evening preference and weight loss resistance in a
behavioral therapy treatment for obesity. Int J Obes . 2012;36:1436-1441.
231. Garaulet M, Sanchez-Moreno C, Smith CE, et al. Ghrelin, sleep reduction and evening
preference: relationships to CLOCK 3111 T/C SNP and weight loss. PLoS One .
2011;6:e17435.
232. Tsuzaki K, Kotani K, Sano Y, et al. The association of the Clock 3111 T/C SNP with
lipids and lipoproteins including small dense low-density lipoprotein: results from the
Mima study. BMC Med Genet . 2010;11:150.
233. Monteleone P, Tortorella A, Docimo L, et al. Investigation of 3111T/C polymorphism
of the CLOCK gene in obese individuals with or without binge eating disorder: asso-
ciation with higher body mass index. Neurosci Lett . 2008;435:30-33.
234. Sookoian S, Castano G, Gemma C, Gianotti TF, Pirola CJ. Common genetic variations
in CLOCK transcription factor are associated with nonalcoholic fatty liver disease.
World J Gastroenterol . 2007;13:4242-4248.
235. Dupuis J, Langenberg C, Prokopenko I, et al. New genetic loci implicated in fasting
glucose homeostasis and their impact on type 2 diabetes risk. Nat Genet .

2010;42:105-116.
236. Kelly MA, Rees SD, Hydrie MZ, et al. Circadian gene variants and susceptibility to
type 2 diabetes: a pilot study. PLoS One . 2012;7:e32670.
237. Garcia-Rios A, Perez-Martinez P, Delgado-Lista J, et al. A Period 2 genetic variant
interacts with plasma SFA to modify plasma lipid concentrations in adults with meta-
bolic syndrome. J Nutr . 2012;142:1213-1218.
238. Goumidi L, Grechez A, Dumont J, et al. Impact of REV-ERB alpha gene polymor-
phisms on obesity phenotypes in adult and adolescent samples. Int J Obes .

2013;37:666-672.
239. Chatham JC, Young ME. Regulation of myocardial metabolism by the cardiomyocyte
circadian clock. J Mol Cell Cardiol . 2013;55:139-146.
240. Morris CJ, Yang JN, Scheer FA. The impact of the circadian timing system on cardio-
vascular and metabolic function. Prog Brain Res . 2012;199:337-358.