The Circadian Clock in Cancer Development and Therapy - Progress in Molecular Biology and Translational Science - page 260

5. Takahashi JS, Hong HK, Ko CH, McDearmon EL. The genetics of mammalian cir-
cadian order and disorder: implications for physiology and disease. Nat Rev Genet .
Oct 2008;9(10):764-775.
6. Sahar S, Sassone-Corsi P. Metabolism and cancer: the circadian clock connection. Nat
Rev Cancer . 2009;9(12):886-896.
7. Padmanabhan K, Robles MS, Westerling T, Weitz CJ. Feedback regulation of tran-
scriptional termination by the mammalian circadian clock PERIOD complex. Science .
2012;337(6094):599-602.
8. Preitner N, Damiola F, Lopez-Molina L, et al. The orphan nuclear receptor REV-
ERBalpha controls circadian transcription within the positive limb of the mammalian
circadian oscillator. Cell . 2002;110(2):251-260.
9. Cho H, Zhao X, Hatori M, et al. Regulation of circadian behaviour and metabolism by
REV-ERB-alpha and REV-ERB-beta. Nature . 2012;485(7396):123-127.
10. Sato TK, Panda S, Miraglia LJ, et al. A functional genomics strategy reveals Rora as a
component of the mammalian circadian clock. Neuron . 2004;43(4):527-537.
11. Duong HA, Robles MS, Knutti D, Weitz CJ. A molecular mechanism for circadian
clock negative feedback. Science . 2011;332(6036):1436-1439.
12. Nakahata Y, Kaluzova M, Grimaldi B, et al. The NAD -dependent deacetylase

SIRT1 modulates CLOCK-mediated chromatin remodeling and circadian control.
Cell . 2008;134(2):329-340.
13. Asher G, Gatfield D, Stratmann M, et al. SIRT1 regulates circadian clock gene expres-
sion through PER2 deacetylation. Cell . 2008;134(2):317-328.
14. Feng D, Liu T, Sun Z, et al. A circadian rhythm orchestrated by histone deacetylase 3
controls hepatic lipid metabolism. Science . 2011;331(6022):1315-1319.
15. Stratmann M, Suter DM, Molina N, Naef F, Schibler U. Circadian Dbp transcription
relies on highly dynamic BMAL1-CLOCK interaction with E boxes and requires the
proteasome. Mol Cell . 2012;48(2):277-287.
16. Akhtar RA, Reddy AB, Maywood ES, et al. Circadian cycling of the mouse liver trans-
criptome, as revealed by cDNA microarray, is driven by the suprachiasmatic nucleus.
Curr Biol . 2002;12(7):540-550.
17. Duffield GE, Best JD, Meurers BH, Bittner A, Loros JJ, Dunlap JC. Circadian programs
of transcriptional activation, signaling, and protein turnover revealed by microarray
analysis of mammalian cells. Curr Biol . 2002;12(7):551-557.
18. Hughes ME, DiTacchio L, Hayes KR, et al. Harmonics of circadian gene transcription
in mammals. PLoS Genet . Apr 2009;5(4):e1000442.
19. Miller BH, McDearmon EL, Panda S, et al. Circadian and CLOCK-controlled regu-
lation of the mouse transcriptome and cell proliferation. Proc Natl Acad Sci USA .
2007;104(9):3342-3347.
20. Panda S, Antoch MP, Miller BH, et al. Coordinated transcription of key pathways in
the mouse by the circadian clock. Cell . 2002;109(3):307-320.
21. Storch KF, Lipan O, Leykin I, et al. Extensive and divergent circadian gene expression
in liver and heart. Nature . 2002;417(6884):78-83.
22. Geyfman M, Kumar V, Liu Q, et al. Brain and muscle Arnt-like protein-1 (BMAL1)
controls circadian cell proliferation and susceptibility to UVB-induced DNA damage in
the epidermis. Proc Natl Acad Sci USA . 2012;109(29):11758-11763.
23. KhapreRV, KondratovaAA, SusovaO, KondratovRV. Circadian clock proteinBMAL1
regulates cellular senescence in vivo. Cell Cycle . 2011;10(23): 4162-4169.
24. Mohawk JA, Green CB, Takahashi JS. Central and peripheral circadian clocks in mam-
mals. Annu Rev Neurosci . 2012;35:445-462.
25. Golombek DA, Rosenstein RE. Physiology of circadian entrainment. Physiol Rev .
2010;90(3):1063-1102.
26. Do MT, Yau KW. Intrinsically photosensitive retinal ganglion cells. Physiol Rev .
2010;90(4):1547-1581.

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