Doxil — The First FDA-Approved Nano-Drug: From an Idea to a Product - Harnessing Biomaterials in Nanomedicine: Preparation, Toxicity, and Applications - page 387

Amselem, S., Gabizon, A. and Barenholz, Y., Evaluation of a new extrusion
device for the production of stable oligolamellar liposomes in a liter
scale. J. Liposome Res . 1 , 287-301 (1989-90).
Amselem, S., Gabizon, A., and Barenholz, Y., Optimization and upscaling of
doxorubicin-containing liposomes for clinical use. J. Pharm. Sci . 79 ,
1045-1052 (1990).
Amselem, S., Gabizon, A., and Barenholz, Y., A large-scale method for the
preparation of sterile and nonpyrogenic liposomal formulations of
defined size distributions for clinical use, in Liposome Technology ,
2nd Edition, Vol. I, Liposome Preparation and Related Techniques
(Gregoriadis, G., ed.), CRC Press, Boca Raton, FL, pp. 501-525
(1993b).
Andrews, P.A., Brenner, D.E., Chou, F.T., Kubo, H., Bachur, N.R., Facile and
definitive determination of human Adriamycin and Daunorubicin
metabolites by high-pressure liquid chromatography, Drug Metab.
Dispos ., 8 , 152-156 (1980).
Avnir, Y., Ulmansky, R., Wasserman, V., Even-Chen, S., Broyer, M., Barenholz,
Y., and Naparstek, Y., Amphipathic weak acid glucocorticoid prodrugs
remote loaded into nano sterically stabilized liposomes: a novel
approach to treat autoimmune arthritis. Arthritis Rheum., 58 (1), 119-
129 (2008).
Bandak, S., Ramu, A., Barenholz, Y., and Gabizon A., Reduced UV-induced
degradation of doxorubicin encapsulated in polyethylene glycol-coated
liposomes, Pharm. Res . 16 , 841-846 (1999).
Bangham, A.D., Liposomes: the Babraham connection, Chem. Phys. Lipids 64 ,
275-285 (1993).
Barenholz, Y., Liposome production: historic aspects. In: Liposome Dermatics
(Braun-Falco, O., Korting, H.C., and Maibach, H.I., eds.), Springer Verlag,
Berlin, pp. 69-81 (1992).
Barenholz, Y., Design of liposome-based drug carriers: from basic research
to application as approved drugs. In: Medical Applications of Liposomes.
(Lasic, D.D., and Papahadjopoulos, D. eds.) Elsevier Science, Amsterdam,
541-565 (1998).
Barenholz, Y., Liposome application: problems and prospects. Curr. Opin.
Colloid Interface Sci. 6 , 66-77 (2001).
Barenholz, Y., Relevancy of drug loading to liposomal formulation therapeutic
efficacy, J. Liposome Res , 13 , 1-8 (2003).
Barenholz, Y. Amphipathic weak base loading into preformed liposomes
having a transmembrane ammonium ion gradient: from the bench to
approved Doxil. In: Liposome Technology , 3rd Edition, Gregoriadis, G.,
ed., Vol. II, Informa Healthcare, New York, pp. 1-26 (2007).