Zebrafish: A New In Vivo Model for Identifying P-Glycoprotein Efflux Modulators - Zebrafish: Methods for Assessing Drug Safety and Toxicity - page 182

REFERENCES
A NNILO T, C HEN ZQ, S HULENIN S, C OSTANTINO J, T HOMAS L, L OU H, S TEFANOV S, and D EAN M (2006).
Evolution of the vertebrate ABC gene family: analysis of gene birth and death. Genomics 88(1): 1-11.
B AUER B, H ARTZ AM, F RICKER G, andM ILLER DS (2005). Modulation of p-glycoprotein transport function at
the blood-brain barrier. Exp Biol Med (Maywood) 230(2): 118-127.
B EGLEY DJ (2004). ABC transporters and the blood-brain barrier. Curr Pharm Des 10(12): 1295-1312.
B RESOLIN T, DE F REITAS R EBELO M, and C ELSO D IAS B AINY A (2005). Expression of PXR, CYP3A and MDR1
genes in liver of zebrafish. Comp Biochem Physiol C Toxicol Pharmacol 140(3-4): 403-407.
C HOO EF, K URNIK D, M USZKAT M, O HKUBO T, S HAY SD, H IGGINBOTHAM JN, G LAESER H, K IM RB, W OOD AJ,
and W ILKINSON GR (2006). Differential in vivo sensitivity to inhibition of P-glycoprotein located in
lymphocytes, testes, and the blood-brain barrier. J Pharmacol Exp Ther 317(3): 1012-1018.
C HOO EF, L EAKE B, W ANDEL C, I MAMURA H, W OOD AJ, W ILKINSON GR, and K IM RB (2000). Pharmacological
inhibition of P-glycoprotein transport enhances the distribution of HIV-1 protease inhibitors into brain
and testes. Drug Metab Dispos 28(6): 655-660.
C SERR HF and B UNDGAARD M (1984). Blood-brain interfaces in vertebrates: a comparative approach. Am J
Physiol 246 (3 Pt 2): R277-R288.
DE V RIES HE, K UIPER J, DE B OER AG, V AN B ERKEL TJ, and B REIMER DD (1997). The blood-brain barrier in
neuroinflammatory diseases. Pharmacol Rev 49(2): 143-155.
D EAN M, R ZHETSKY A, and A LLIKMETS R (2001). The human ATP-binding cassette (ABC) transporter
superfamily. Genome Res 11(7): 1156-1166.
F ARDEL O, C OURTOIS A, D RENOU B, L AMY T, L ECUREUR V, LE P RISE PY, and F AUCHET R (1996). Inhibition of
P-glycoprotein activity in human leukemic cells by mifepristone. Anticancer Drugs 7(6): 671-677.
F ONTAINE M, E LMQUIST WF, andM ILLER DW(1996). Use of rhodamine 123 to examine the functional activity
of P-glycoprotein in primary cultured brain microvessel endothelial cell monolayers. Life Sci 59(18):
1521-1531.
G RUOL DJ, Z EE MC, T ROTTER J, andB OURGEOIS S (1994). Reversal of multidrug resistance byRU486. Cancer
Res 54(12): 3088-3091.
H AMILTON KO, T OPP E,M AKAGIANSAR I, S IAHAAN T, Y AZDANIAN M, andA UDUS KL(2001).Multidrug resistance-
associated protein-1 functional activity in Calu-3 cells. J Pharmacol Exp Ther 298(3): 1199-1205.
H UNG C-C, C HEN C-C, L IN C-J, and L IOU H-H (2008). Functional evaluation of polymorphisms in the
human ABCB1 gene and the impact on clinical responses of antiepileptic drugs. Pharmacogenetics &
Genomics 18: 390-402.
I SOGAI S, H ORIGUCHI M, and W EINSTEIN BM (2001). The vascular anatomy of the developing zebrafish: an
atlas of embryonic and early larval development. Dev Biol 230(2): 278-301.
J EONG JY, K WON HB, A HN JC, K ANG D, K WON SH, P ARK JA, and K IM KW (2008). Functional and
developmental analysis of the blood-brain barrier in zebrafish. Brain Res Bull 75(5): 619-628.
K EMPER EM, VAN Z ANDBERGEN AE, C LEYPOOL C, M OS HA, B OOGERD W, B EIJNEN JH, and VAN T ELLINGEN O
(2003). Increased penetration of paclitaxel into the brain by inhibition of P-Glycoprotein. Clin Cancer
Res 9(7): 2849-2855.
K EMPER EM, V ERHEIJ M, B OOGERD W, B EIJNEN JH, and VAN T ELLINGEN O (2004). Improved penetration of
docetaxel into the brain by co-administration of inhibitors of P-glycoprotein. Eur J Cancer 40(8):
1269-1274.
L I DQ, W ANG ZB, B AI J, Z HAO J, W ANG Y, H U K, and D U YH (2004). Reversal of multidrug resistance in
drug-resistant human gastric cancer cell line SGC7901/VCR by antiprogestin drug mifepristone. World J
Gastroenterol 10(12): 1722-1725.
L OSCHER W and P OTSCHKA H (2005). Blood-brain barrier active efflux transporters: ATP-binding cassette
gene family. NeuroRx 2(1): 86-98.
M AHAR D OAN KM, H UMPHREYS JE, W EBSTER LO, W RING SA, S HAMPINE LJ, S ERABJIT -S INGH CJ, A DKISON KK,
and P OLLI JW (2002). Passive permeability and P-glycoprotein-mediated efflux differentiate central
nervous system (CNS) and non-CNS marketed drugs. J Pharmacol Exp Ther 303(3): 1029-1037.
M AINES LW, A NTONETTI DA, W OLPERT EB, and S MITH CD (2005). Evaluation of the role of P-glycoprotein in
the uptake of paroxetine, clozapine, phenytoin and carbamazapine by bovine retinal endothelial cells.
Neuropharmacology 49(5): 610-617.
M C G RATH P, P ARNG C, and S ERBEDZIJA G (2010). Methods of screening agents using teleosts, US Patent
7,767,880, issued August 2010.