Biomedical Engineering Reference
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Fig. 2 Normalized percentage change in strain (a and b), active tension (c and d), work rate
(e and f) and total activation time (g and h) for pacing on the endocardium ( left panels ) and
epicardium ( right panels ). Blue (grey) to red (dark gray) correspond to the worst to best response
to be in the same location for both endocardial or epicardial pacing (excepting cases of
epi or endocardial scarring). Clinical trials have shown better responses with endocar-
dial pacing [ 2 ], although this may be due to the limited number of pacing sites that can
be reached due to the coronary anatomy rather than an indication that pacing from the
endocardium or epicardium is intrinsically better.
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