Deoxyribozyme-Based Molecular Computation - DNA Nanotechnology: From Structure to Function - page 347

Fig. 17.3 ( a ) The layout of molecular logic in a well for tit-for-tat game before training; all four
wells contain identical molecular logic units. ( b ) An example of a complete training session
using the “clockwise” strategy. In board representation, the human's potential new moves are
represented by black with a word “if” inside, previous moves by gray • , while the automaton's

potential first moves are represented by gray . At the end of the training procedure, the training

inputs t 13 ,t 22 ,t 23 were added into well 1; t 11 ,t 21 ,t 24 into well 2; t 14 ,t 21 ,t 24 into well 3; and
t 12 ,t 22 ,t 23 into well 4. ( c ) The layout of molecular logic in the four wells of the automaton
trained according to a “clockwise” strategy as shown in b (only the trimmed gates are shown,
for simplicity of presentation). ( d ) The game-play for the “clockwise” strategy. The automaton
was trained by a “clockwise” strategy as shown in b . In board representation, the human's new
moves are represented by black , previous moves by gray • , while the automaton's new moves
are represented by black ı and previous moves by gray ı. Inputs triggering these moves are also
indicated

ı