Self-Assembled DNA-Inorganic Nanoparticle Structures - DNA Nanotechnology: From Structure to Function - page 194

Fig. 9.7 3-D nanostructures constructed by precise placement of nanoparticles on 3-D DNA self-
assembled scaffold ( a - c ). Crystalline superlattice assembled from DNA polyvalent nanoconjugates
as building block ( d ). The scale bars represent 50 nm (Part ( a ) reprinted with permission from
Ref. [ 49 ]. Copyright 2009 American Chemical Society. Part ( b ) reprinted by permission from
Macmillan Publishers Ltd: Ref. [ 52 ], copyright 2012. Part ( c ) reproduced from Ref. [ 55 ]by
permission of John Wiley & Sons Ltd. Part ( d ) reprinted by permission from Macmillan Publishers
Ltd: Ref. [ 61 ], copyright 2010)
Both left-handed and right-handed helical arrangements of AuNPs were achieved
in their work. Ding successfully synthesized 3-D helical gold nanostructures by
using 2-D rectangular DNA origami as the initial template [ 53 ]. AuNPs were first
positioned on the initial template into two linear chains, subsequently rolled into 3-D
helical arrangements by the addition of the folding strand, which hybridized with
the two opposite edges of the rectangular origami sheet and led to the formation of
hollow origami tube. These rationally designed helical gold nanostructures exhibit