Biomedical Engineering Reference
In-Depth Information
7.5
Conclusion
This chapter reflected a collection of tools for DNA analysis with the aid of
microfluidics: from thermal cycling to isothermal reaction, from complexity to
simplicity, from single to multiple, from high cost to low cost, and from concept
to application. Technical development produced the microfluidic tools, and the
tools bring researcher some new insight guiding us to explore new applications
previously unavailable. Further development of microfluidic tools for DNA analysis
requires more inspirations from biological studies and events happened in small
scale. The challenges and breakthrough of this field in the near future may mainly
depend on the researchers' (as well as collaborative groups') deep understanding
for remaining basic biological or medical problems, such as the fundamental
mechanisms of major diseases, and the discovery of molecular mechanisms of many
physiological/biochemical processes.
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