Biomedical Engineering Reference
In-Depth Information
A chemical biosensor is a sensor that produces an electrical signal proportional
to the concentration of biochemical analytes. These biosensors use chemical as
well as physical principles in their operation [ 10 , 11 ]. Interdisciplinary studies in
chemistry, electronics, and biology have led to the development of novel sensor
interfaces. Based on unique physical, chemical, and electrocatalytic properties,
nanoparticles play variety of roles in different biosensing systems. The attachment
of nanoparticles onto electrodes drastically enhances the conductivity and electron
transfer from the redox analytes to make them electroanalytical sensor [ 12 ].
Interface
Physical
Sensor
Chemical
Sensor
Biosensor Schematic
Figure 6.2 describes a typical biosensor configuration that allows measurement
of a target analyte without using reagents. The device incorporates a biological-
sensing element with a traditional transducer.
Fig. 6.2
A biosensor configuration
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