Biomedical Engineering Reference
In-Depth Information
to suggest that resultant changes in functional properties are either unhelpful or neutral.
Ingredients encapsulated in SLN tend to be more prone to chemical degradation compared
to the same ingredients in liquid oil nanoemulsions. Furthermore, SLN seem to be less
physically stable than liquid oil nanoemulsions (particularly in the
-polymorph). It may be
that the most effective use of SLN will be for ingredients designed to react quickly, perhaps
antioxidants, or to promote adsorption.
β
ACKNOWLEDGEMENT
This work was supported by a grant from the USDA-AFRI program (Award number: 2009-
65503-05960, Program code: 93430).
REFERENCES
Acosta E. 2009 . Bioavailability of nanoparticles in nutrient and nutraceutical delivery . Curr. Opin Colloid
Interface Sci 14 ( 1 ): 3 - 15 .
Ahlin P , Julijana K , Slavko P , Janez S , Marjeta S . 2003 . The effect of lipophilicity of spin-labeled compounds
on their distribution in solid lipid nanoparticle dispersions studied by electron paramagnetic resonance.
J Pharm Sci 92 ( 1 ): 58 - 66 .
Amar I , Aserin A , Garti N . 2003 . Solubilization patterns of lutein and lutein esters in food grade nonionic
microemulsions. J Agric Food Chem 51 ( 16 ): 4775 - 4781 .
Anton N , Benoit JP , Saulnier P . 2008 . Design and production of nanoparticles formulated from nano-
emulsion templates - A review . J Control Release 128 : 185 - 199 .
Arboleya JC , Sutcliffe LH , Wilde PJ , Fairhust SA . 2005 . Density and microviscosity studies of palm oil/
water emulsions . J Agric Food Chem 53 ( 11 ): 4448 - 4453 .
Awad TS , Sato K . 2002 . Acceleration of crystallisation of palm kernel oil in oil-in-water emulsion by
hydrophobic emulsifier additives . Colloids Surf B-Biointerfaces 25 ( 1 ): 45 - 53 .
Awad TS , Helgason T , Kristbergsson K , Decker EA , Weiss J , McClements DJ . 2008 . Effect of cooling and
heating rates on polymorphic transformations and gelation of tripalmitin solid lipid nanoparticle (SLN)
suspensions. Food Biophys 3 : 155 - 162 .
Bonacucina G , Cespi M , Misici-Falzi M , Palmieri GF . 2009 . Collodal soft matter as drug delivery system.
J Pharm Sci 98 ( 1 ): 1 - 42 .
Boon CS , Xu Z , Yue X , McClements DJ , Weiss J , Decker EA . 2008 . Factors affecting lycopene oxidation in
oil-in-water emulsions . J Agric Food Chem 56 ( 4 ): 1408 - 1414 .
Bunjes H , Koch MHJ . 2005 . Saturated phospholipids promote crystallization but slow down polymorphic
transitions in triglyceride nanoparticles. J Control Release 107 : 229 - 243 .
Bunjes H , Unruh T . 2007 . Characterization of lipid nanoparticles by differential scanning calorimetry, x-ray
and neutron scattering. Adv Drug Deliv Rev 59 : 379 - 402 .
Bunjes H , Westesen K . 2001 . Influences of colloidal state on physical properties of solid fats . In: Garti N &
Sato K (editors). Crystallization Processes in Fats and Lipid Systems. New York: Marcel Dekker, Inc.
pp. 457 - 484 .
Bunjes H , Westesen K , Koch MHJ . 1996 . Crystallization tendency and polymorphic transitions in triglyceride
nanoparticles. Int J Pharm 129 : 159 - 173 .
Bunjes H , Koch MHJ , Westesen K . 2000 . Effect of particle size on colloidal solid triglycerides . Langmuir
16 : 5234 - 5241 .
Bunjes H , Drechsler M , Koch MHJ , Westesen K . 2001 . Incorporation of the model drug Ubidecarenone into
solid lipid nanoparticles. Pharm Res 18 ( 3 ): 287 - 293 .
Bunjes H , Koch MHJ , Westesen K . 2002 . Effects of surfactants on the crystallization and polymorphism of
lipid nanoparticles. ProgColloid PolymSci 121 : 7 - 10 .
Bunjes H , Koch MHJ , Westesen K . 2003 . Influence of emulsifiers on the crystallization of solid lipid
nanoparticles. J Pharm Sci 92 ( 7 ): 1509 - 1520 .
Bunjes H , Steiniger F , Richter W . 2007 . Visualizing the structure of triglyceride nanoparticles in different
crystal modification. Langmuir 23 ( 7 ): 4005 - 4012 .
Search WWH ::
Custom Search