Biomedical Engineering Reference
In-Depth Information
QCM
MAA SAMs
COO
-
COO
-
COO
-
COO
-
COO
-
Chitosan
S
S
S
S
S
+
+
+
+
+
+
+
+
+
+
+
COO
-
COO
-
COO
-
COO
-
COO
-
NaCl/NaOH
solution
S
S
S
S
S
Immobilization of
alginate-(anti-HSA antibody)
Ag
Ag
Ag
Ag
Ab
Ab
Ab
Ab
Ab
Ab
Ab
Ab
Ab
Ab
Ab
Ab
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
+
-
+
-
+
+
+
+
+
+
+
+
+
+
+
Antigen-antibody
immunoreaction
+
+
+
+
+
+
+
+
+
COO
-
COO
-
COO
-
COO
-
COO
-
COO
-
COO
-
COO
-
COO
-
COO
-
S
S
S
S
S
S
S
S
S
S
Figure 4.21
Schematic diagram of the immunoassay procedures. (From Deng, T. et al. 2005.
Anal Chim Acta
532: 137-144.
With permission.)
ALG, CHI....
adsorption
Core
removal
DOX
release
Hollow shell
DOX-shell
ALG
CHI
DOX
Figure 4.22
Schematic illustration of the procedure for the loading and release of doxorubicin (DOX) in the LBL self-assem-
bled chitosan-alginate shells. (From Tao, X. et al. 2007.
Int J Pharm
336: 376-381. With permission.)
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