Bioactivities of Chitosan and Its Derivatives - Chitosan Based Hydrogels: Functions and Applications - page 174

215. Lee, E., Lee, J., Lee, I. H., Yu, M., Kim, H., Chae, S. Y., and Jon, S. 2008. Conjugated chitosan as
a novel plat form for oral delivery of paclitaxel. J Med Chem 51: 6442-6449.
216. Kim, Y. H., Gihm, S. H., and Park, C. R. 2001. Structural characteristics of size-controlled
self-aggregates of deoxycholic acid-modified chitosan and their application as a DNA delivery
carrier. Bioconj Chem 12: 932-938.
217. Lee, K. Y., Kim, J. H., Kwon, L. C., and Jeong, S. Y. 2000. Self-aggregates of deoxycholic acid-
modified chitosan as a novel carrier of adriamycin. Colloid Polym Sci 2278: 1216-1219.
218. Gaucher, G., Dufresne, M. H., Sant, V. P., Kang, N., Maysinger, D., and Leroux, J. C. 2005. Block
copolymer micelles: preparation, characterization and application in drug delivery. J Control
Release 109: 169-188.
219. Omelyaneko, V., Kopeckova, P., Gentry, C., and Kopecek, J. 1998. Targetable HPMA copolymer
adriamycin conjugates. Recognition, internalization, and subcellular fate. J Control Release
53: 25-37.
220. Park, J. H., Kwon, S., Lee, M., Chung, H., Kim, J. H., Kim, Y. S., Park, R. W., Kim, I. S., Seo, S. B.,
Kwon, I. C., and Jeong, S. Y. 2006. Self-assembled nanoparticles based on glycolchitosan bear-
ing hydrophobic moieties as carriers for doxorubicin: in vivo biodistribution and anti-tumor
activity. Biomaterials 27: 119-126.
221. Chytil, P., Etrych, T., Konak, C., Sirova, M., Mrkvan, T., and Rihova, B. 2006. Properties of
HPMA copolymer-doxorubicin conjugates with pH-controlled activation: effect of polymer
chain modification. J Control Release 115: 26-36.
222. Teodori, E., Dei, S., Scapecchi, S., and Gualtieri, F. 2002. The medicinal chemistry of multi drug
resistance (MDR) reversing drugs. IL Farmaco 57: 385-415.
223. Tijerina, M., Fowers, K. D., Kopeckova, P., and Kopecek, J. 2000. Chronic exposure of human
ovarian carcinoma cells to free or HPMA copolymer-bound mesochlorin does not induce
P-glycoprotein-mediated multi drug resistance. Biomaterials 21: 2203-2210.
224. Gottesman, M. M., Fojo, T., and Bates, S. E. 2002. Multi drug resistance in cancer: Role of ATP-
dependent transporters. Nat Rev Cancer 2: 48-58.
225. Kabanov, A. V., Batrakova, E. V., and Alakhov, V. Y. 2002. Pluronic block copolymers for over-
coming drug resistance in cancer. Adv Drug Deliv Rev 54: 759-779.
226. Stastny, M., Strohalm, J., Plocova, D., Ulbrich, K., and Rihova, B. 1999. A possibility to over-
come P-glycoprotein (PGP)-mediated multi drug resistance by antibody-targeted drugs con-
jugated to N -(2-hydroxypropyl)methacrylamide (HPMA) copolymer carrier. Eur J Cancer 35:
459-66.
227. Hu, F. Q., Liu, L. N., Du, Y. Z., and Yuan, H. 2009. Synthesis and antitumor activity of doxo-
rubicin conjugated stearic acid-g-chitosan oligosaccharide polymeric micelles. Biomaterials
30: 1-9.
228. Prabaharan, M., Grailer, J. J., Pilla, S., Steeber, D. A., and Gong, S. 2009. Folate-conjugated
amphiphilic hyperbranched block copolymers based on Boltorn H40, poly-(L-lactide) and
poly (ethyleneglycol) for tumor-targeted drug delivery. Biomaterials 30: 3009-3019.
229. Kawano, K., Watanabe, M., Yamamoto, T., Yokoyama, M., Opanasopit, P., Okano, T., and
Maitani, Y. 2006. Enhanced antitumor effect of camptothecin loaded in long-circulating poly-
meric micelles. J Control Release 112: 329-332.
230. Watanabe, M., Kawano, K., Yokoyama, M., Opanasopit, P., Okano, T., and Maitani, Y. 2006.
Preparation of camptothecin-loaded polymeric micelles and evaluation of their incorporation
and circulation stability. Int J Pharm 308: 183-189.
231. Matsumura, Y. and Maeda, H. 1986. A new concept for macromolecular therapeutics in cancer
chemotherapy: Mechanism of tumoritropic accumulation of proteins and antitumor agent
smancs. Cancer Res 46: 6387-6392.
232. Maeda, H., Wu J., Sawa, T., Matsumura, Y., and Hori, K. 2000. Tumor vascular permeability and
the EPR effect in macromolecular therapeutics: A review. J Control Release 65: 271-284.
233. Min, K. H., Park, K., Kim, Y. S., Bae, S. M., Lee, S., Jo, H. G., Park, R. W., Kim, I. S., and Jeong, S. Y.
2008. Hydrophobically modified glycol chitosan nanoparticles-encapsulated camptothecin
enhance the drug stability and tumor targeting in cancer therapy. J Control Release 27: 208-218.