Biomedical Engineering Reference
In-Depth Information
Chapter2
BiomedicalApplicationsofEmission
Tomography
Michael Schafers, Sven Hermann, Sonja Schafers, Thomas Viel,
Marilyn Law, and Andreas H. Jacobs
European Institute for Molecular Imaging, University of Munster, Munster,
Germany
2.1
The role of imaging in biomedical research and applications ::::
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2.2
Functional and molecular imaging by emission tomography
enables high sensitivity and spatial resolution ::::::::::::::::::
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2.3
Biomedical applications of emission tomography depend on
tracers :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
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2.4
Applications ::::::::::::::::::::::::::::::::::::::::::::::::::::::
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2.4.1
Preclinical applications ::::::::::::::::::::::::::::::::::
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2.4.2
Clinical applications :::::::::::::::::::::::::::::::::::::
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2.4.3
Examples of biomedical applications of emission
tomography ::::::::::::::::::::::::::::::::::::::::::::::
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2.4.3.1
Bioluminescence imaging of tumor growth :::
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2.4.3.2
Dynamic PET in pharmakodynamic studies :
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2.4.3.3
From mice to men|Non-invasive
translational imaging of inflammatory
activity in graft-versus-host disease :::::::::: 20
2.4.3.4
PET to quantify catecholamine recycling and
receptor density in patients with arrhythmias
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2.4.3.5
Multiparametric imaging of brain tumors :::
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References :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
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2.1 The role of imaging in biomedical research and
applications
Over the past decades imaging has gained an increasingly important role
in biomedical research and clinical decision making [30, 31]. This is mostly
due to the specific strength and beauty of imaging, which is (in the majority
of imaging techniques) the non-destructive multi-parametric characterization
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