Biomedical Engineering Reference
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Fig. 2 ( a ) Schematic of a multifunctional quantum dot probe showing the capping ligand TOPO
and an outer co-polymer layer, which could be coupled to affi nity ligands or PEG. ( b ) Conjugation
of QDs to biomolecules (a) through covalent cross-linking using EDAC (b) binding anti-body frag-
ments via reduced sulfhydryl-amine coupling with SMCC (c) by means of an adaptor protein
(d) conjugation of histidine-tagged peptides to Ni-NTA modifi ed QDs. Source : Gao et al. ( 2005 )
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