Biomedical Engineering Reference
In-Depth Information
Fig. 2
(
a
) Schematic of a multifunctional quantum dot probe showing the capping ligand TOPO
and an outer co-polymer layer, which could be coupled to affi nity ligands or PEG. (
b
) Conjugation
of QDs to biomolecules (a) through covalent cross-linking using EDAC (b) binding anti-body frag-
ments via reduced sulfhydryl-amine coupling with SMCC (c) by means of an adaptor protein
(d) conjugation of histidine-tagged peptides to Ni-NTA modifi ed QDs.
Source
: Gao et al. (
2005
)
