Biomedical Engineering Reference
at the site quickly self-assembled into a dense mesh nanofi ber network sponge that
instantly blocked the rushing of the liquid. It may be perhaps nano-mechanics rather
The development of new biological materials, particularly those biologically
inspired nanoscale scaffolds mimicking in vivo environment, that serve as permis-
sive substrates for cell growth, differentiation and biological function is an actively
pursued area, which in turn could signifi cantly advance regenerative medicine.
These materials will be useful not only for further understanding of cell biology in
3-D environment but also for advancing medical technology, regenerative biology
Acknowledgments We gratefully acknowledge the supports by grants from Olympus Corp.,
Japan; Menicon, Ltd, Japan and fellowship to FG from Fondazione Centro San Raffaele del Monte
Tabor, Milan, Italy.
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