Biomedical Engineering Reference
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suppression, and stimulation of caspase-dependent cell death. Mol. Cell. Biol.
28, 529-538.
Knobloch, J., Shaughnessy, J.D., Jr., and Ruther, U. (2007) Thalidomide
induces limb deformities by perturbing the Bmp/Dkk1/Wnt signaling
pathway. FASEB J 21, 1410-1421.
Koop, D.R. (2006) Alcohol metabolism's damaging effects on the cell: a focus
on reactive oxygen generation by the enzyme cytochrome P450 2E1.
Alcohol Res. Health 29, 274-280.
Kotch, L.E. and Sulik, K.K. (1992) Experimental fetal alcohol syndrome:
proposed pathogenic basis for a variety of associated facial and brain
anomalies. Am. J. Med. Genet. 44, 168-176.
Kunitoh, S., Tanaka, T., Imaoka, S., Funae, Y., and Monna, Y. (1993) Contribu-
tion of cytochrome P450s to MEOS (microsomal ethanol-oxidizing system):
a specific and sensitive assay of MEOS activity by HPLC with fluorescence
labeling. Alcohol and Alcohol. (Oxford, Oxfordshire) 1B, 63-68.
Lambeth, J.D. (2004) NOX enzymes and the biology of reactive oxygen. Nat.
Rev. Immunol. 4, 181-189.
Lander, H.M. (1997) An essential role for free radicals and derived species in
signal transduction. FASEB J. 11, 118-124.
Lee, C.J., Goncalves, L.L., and Wells, P.G. (2011) Embryopathic effects of
thalidomide and its hydrolysis products in rabbit embryo culture: evidence
for a prostaglandin H synthase (PHS)-dependent, reactive oxygen species
(ROS)-mediated mechanism. FAS EB J . 25, 2468-2483.
Levine, R.L., Williams, J.A., Stadtman, E.R., and Shacter, E. (1994) Carbonyl
assays for determination of oxidatively modified proteins. Methods
Enzymol 233, 346-357.
Lieber, C.S. (2004) The discovery of the microsomal ethanol oxidizing system
and its physiologic and pathologic role. Drug Metab. Rev. 36, 511-529.
Lu, K., Collins, L.B., Ru, H., Bermudez, E., and Swenberg, J.A. (2010)
Distribution of DNA adducts caused by inhaled formaldehyde is consist-
ent with induction of nasal carcinoma but not leukemia. Toxicol. Sci. 116,
441-451.
Lutwak-Mann, C. (1938) Alcohol dehydrogenase of animal tissues. Biochem.
J. 32, 1364-1374.
Makar, A.B. and Tephly, T.R. (1977) Methanol poisoning VI: role of folic acid
in the production of methanol poisoning in the rat. J. Toxicol. Environ.
Health 2, 1201-1209.
Makar, A.B., Tephly, T.R., and Mannering, G.J. (1968) Methanol metabolism
in the monkey. Mol. Pharmacol. 4, 471-483.
