Biomedical Engineering Reference
In-Depth Information
When human data, especially independent human data, are
available, they should always be utilized to objectively challenge
model predictions.
REFERENCES
Battelle. (2006) Development, Calibration and Application of a Methanol
PBPK Model. Battelle Project No. 48746. Authors: Poet, T.S., Teeguarden
J.G., and Hinderliter, P.M. Final Report dated January 10, 2006. Pacific
Northwest National Laboratory, Center for Biological Monitoring and
Modeling, Richland, WA.
Batterman, S.A., Franzblau, A., D'Arcy, J.B., Sargent, N.E., Gross, K.B., and
Schreck, R.M. (1998) Breath, urine, and blood measurements as biological
exposure indices of short-term inhalation exposure to methanol. Int. Arch.
Occup. Environ. Health 71, 325-335.
Bernillon, P. and Bois, F.Y. (2000) Statistical issues in toxicokinetic model-
ing: A Bayesian perspective. Environ. Health Perspect. 108, (Suppl 5),
883-893.
Bouchard, M., Brunet, R.C., Droz, P.O., and Carrier, G. (2001) A biologically
based dynamic model for predicting the disposition of methanol and its
metabolites in animals and humans. Toxicol. Sci. 64, 169-184.
CERHR (2002) NTP-CERHR Expert Panel Report on the Reproductive and
Developmental Toxicity of Methanol. NTP-CERHR-MeOH-02. April
2002. Center for the Evaluation of Risks to Human Reproduction, Research
Triangle Park, NC.
Clary, J.J. (2003) Methanol, is it a developmental risk to humans? Reg. Toxicol.
Pharmacol. 37, 83-91.
Dorman, D.C., Moss, O.R., Farris, G.M., Janszen, D., Bond, J.A., and
Medinsky, M.A. (1994) Pharmacokinetics of inhaled ( 14 C) methanol and
methanol-derived 14 C formate in normal and folate-deficient cynomolgus
monkeys. Toxicol. Appl. Pharmacol. 128, 229-238.
Dorman, D.C., Bolon, B., Struve, M.F., LaPerle, K.M., Wong, B.A., Elswick,
B., andWelsch, F. (1995) Role of formate in methanol-induced exencephaly
in CD-1 mice. Teratology 52 (1), 30-40.
Ernstgard, L., Shibata, E., and Johanson, G. (2005) Uptake and disposition of
inhaled methanol vapor in humans. Toxicol. Sci. 88 (1), 30-38.
Gelman, A., Bois, F., and Jiang, J. (1996) Physiological pharmacokinetic
analysis using population modeling and informative prior distributions. J.
Am. Stat. Assoc. 91, 1400-1412.
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