Chemistry Reference
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Fig. 10 Synthesis of the first trefoil knot
O
O
Cl
H 2 N
H
N
N
Cl
H 2 N
O
O
CH 2 Cl 2
NEt 3
O
NH
O
O
H
N
O
O
NH
HN
HN
O
NH
N
O
NH
NH
O
O
H
O
H
HN
NH
O
N
O
Fig. 11 Left : Synthesis of a trefoil knot thanks to hydrogen bonding. Right : Crystal structure of
the compound, with the non-covalent interactions indicated by dashed lines
 
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