Biology Reference
In-Depth Information
Figure 5.1
The crucial roles of glutathione.
GSH: Glutathione, Grx: Glutaredoxin, GST:
Glutathione-S transferase, GlxI: Glyoxalase I, GlxII: Glyoxalase II, Fdh1: Glutathione-
dependent formaldehyde dehydrogenase, Fdh2: Formylglutathione hydrolase (esterase).
genes is complex in that
gshA
, which likely arose in cyanobacteria, and
gshB
were acquired independently in present days organisms (
Ashida, Sawa,
& Shibata, 2005
;
Copley & Dhillon, 2002
). All sequenced cyanobacterial
genomes possess the two genes
ghsA
and
gshB
, which are never grouped
into the same gene cluster in spite of the close relation between the GshA
and GshB enzymes (
Table 5.2
). The cyanobacterial
gshB
gene is mostly
