Chemistry Reference
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HO
O
O
O
O
H
FIGURE 10.1
The structure of the important statin monacolin K.
FIGURE 10.2
The oyster mushroom,
Pleurotus ostreatus
, growing on the tree bark pro-
duces monacolin-like compounds. (Courtesy of Steven Foster.)
O
O
O
O
O
O
O
O
O
R
O
O
O
O
O
O
O
Compactin
6-Hydroxy-iso-compactin
5'-Phosphocompactin acid
R=Phosphate moiety
FIGURE 10.3
Structures of statin (monacolin) homologs isolated from natural sources.
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