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O
O
O
R
O
OH
R
+
-2H
2
O
-CO
2
OH
OH
N
OH
NH
2
O
O
O
O
O
R
R
H
2
O
N
NH
2
+
RCHO
N
O
O
O
O
O
O
O
N
HO
HO
NH
2
+
OO
O
O
HO
O
N
O
O
FIGURE 7. 8
Ninhydrin reagent used for detection of amino acids.
1
7
H
6
2
5
3
4
FIGURE 7.9
Basic structure of indole.
R
2
b
R
3
R
3
OH
200-500°C
Catalyst
HO
+
H
R
2
NH
2
R
2
a
R
1
R
1
FIGURE 7.10
Synthetic route to prepare substituted indoles.
NH
2
HO
H
FIGURE 7.11
Structure of the neurotransmitter serotonin.
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