Oral Delivery of Proteins and Peptides: Concepts and Applications - Challenges in Delivery of Therapeutic Genomics and Proteomics - page 518

[92] Merkle HP, Wolany G. Intraoral peptide absorption. In: Audus KL, Raub TJ, edi-
tors. Biological barriers to protein delivery. New York/London: Plenum Press; 1993.
p. 131-60.
[93] Reddy IK, Madan PL. Controlled/sustained release: proteins and peptides. Pharmatimes
1992;58:132-40.
[94] Liaw J, Rojanasakul Y, Robinson JR. The effect of drug charge type and charge density
on corneal transport. Int J Pharm 1992;88:111-24.
[95] Rojanasakul Y, Wang LY, Bhat M, Glover DD, Malanga CJ, Ma JK. The transport bar-
rier of epithelia: a comparative study on membrane permeability and charge selectivity
in the rabbit. Pharm Res 1992;9:1029-34.
[96] Gandhi RB, Robinson JR. Permselective characteristics of rabbit buccal mucosa. Pharm
Res 1991;8:1199-202.
[97] Corbo DC, Huang YC, Chien YW. Nasal delivery of progestational steroid in ovariecto-
mized rabbits. II. Effect of penetrant hydrophilicity. Int J Pharm 1989;50:253-60.
[98] Huang CH, Kimura R, Bawarshi-Nassar R. Mechanism of nasal absorption of drugs
II: absorption of l-tyrosine and the effect of structural modification on its absorption.
J Pharm Sci 1985;74:1298-301.
[99] Hirai S, Yashiki T, Matsuzawa T, Mima H. Absorption of drugs from the nasal mucosa
of rat. Int J Pharm 1981;7:317-25.
[100] Hansen LB, Christrup LL, Bundgaard H. Enhanced delivery of ketobemidone through
porcine buccal mucosa in vitro via more lipophilic ester prodrugs. Int J Pharm 1992;
88:237-42.
[101] Hansen LB, Jorgensen A, Rasmussen SN, Christrup LL, Bundgaard H. Buccal absorption
of ketobemidone and various ester prodrugs in the rat. Int J Pharm 1992;88:243-50.
[102] Corbo DC, Liu JC, Chien YW. Drug absorption through mucosal membranes: effect of
mucosal route and penetrant hydrophilicity. Pharm Res 1989;6:848-52.
[103] Beckett AH, Moffat AC. Correlation of partition coefficients in n -heptane aqueous sys-
tems with buccal absorption data for a series of amines and acids. J Pharm Pharmacol
1969;21:144S-150S.
[104] Beckett AH, Moffat AC. Kinetics of buccal absorption of some carboxylic acids and
the correlation of the rate constants and n -heptane: aqueous phase partition coefficients.
J Pharm Pharmacol 1970;22:15-19.
[105] Toniolo C, Bonora GM, Stavropoulos G, Cordopatis P, Theodoropoulos D. Self-asso-
ciation and solubility of peptides: solvent-titration study of N-protected C-terminal
sequences of substance P. Biopolymers 1986;25:281-9.
[106] Touitou E. Enhancement of intestinal peptide absorption. J Control Release
1992;21:139-44.
[107] Banga AK, Chien YW. Systemic delivery of therapeutic peptides and proteins. Int J
Pharm 1988;48:15-50.
[108] Chien YW, Banga AK. Potential developments in systemic delivery of insulin. Drug
Dev Ind Pharm 1989;15:1601-34.
[109] Conradi RA, Hilgers AR, Ho NFH, Burton PS. The influence of peptide structure on
transport across CACO-2 cells. Pharm Res 1991;8:1453-60.
[110] Conradi RA, Hilgers AR, Ho NFH, Burton PS. The influence of peptide structure on
transport across CACO-2 cells-II. Peptide bond modification which results in improved
permeability. Pharm Res 1992;9:435-9.
[111] Burton PS, Conradi RA, Hilgers AR, Ho NFH, Maggiora LL. The relationship between
peptide structure and transport across epithelial cell monolayers. J Control Release
1992;19:87-98.