Biomedical Engineering Reference
In-Depth Information
Region
Length (m)
Absorbing
Surface Area
(m
2
)
Absorption
Pathway
Transit (or
Residence)
Time of Solids (h)
pH
Enzymes and Others
Microorganism
(Counts/g
Content)
Fasted
Fed
10
2
Stomach
0.2
0.1
P, C, A
1-3
1.5-3
2-5
Pepsin, lipases,
rennin, HCl, cathepsin
Small intestine
7
12
3-5
10
2
Duodenum
0.3
0.1
P, C, A, F, I, E
5.5
5
Bile acids, trypsin,
a-chymotrypsin, and
other peptidases,
amylase, maltase,
proteases, lipases,
nucleases
10
5
Jejunam
3
60
P, C, A, F, I, E
6.1
No change
Erepsin, amylase,
maltase, lactase,
sucrase, peptidases,
lipases
10
7
Ileum
4
60
P, C, A, F, I, E
7-8
No change
Enteropeptidase
(enterokinase) and
other peptidases,
lipases, nucleases,
nucleotidases
10
11
Large intestine
1.5
0.3
4-16
No change
Cecum
0.06-0.07
0.05
P, C, A, E
5.7
10
11
Colon
1.35
0.25
P, C, E
8.0
Reductases, esterases,
glycosidases,
amidases, sulfatase
Ref.
[35]
, Table 4. (Reprinted with permission from Elsevier)
P: passive diffusion
C: convective transport or aqueous channel transport
A: active transport
F: facilitated transport
I: ion-pair transport
E: entero- or pinocytosis
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