The Cell - Challenges in Delivery of Therapeutic Genomics and Proteomics - page 37

number of anticancer and antiviral drugs. They have been demonstrated to affect bio-
distribution following oral intake of various drugs. The hereditary deficiency of these
transporters may lead to hepatic disorders [125,126] .
1.10 Conclusion
The cell, although a miniscule entity, is self-sufficient and exhibits extreme complex-
ity. A step-by-step exploration in the realm of molecular biology has advanced our
knowledge and understanding of the intracellular fundamentals, opening newer vis-
tas for the application of cellular biology principles in the allied fields of medical
sciences. Knowledge of nuclear chemistry and biology has been one of the great-
est advances of science, instigating an era of treatment at the nuclear and enzymatic
levels for the betterment of mankind in general. The intracellular delivery of pro-
teomics and genomics has been made possible by overcoming and manipulating sev-
eral uncompromising barriers. The following chapters delve into the intricacies of
these concepts and give the reader a panoramic view of the state of art in the field of
genomic and proteomics delivery.
Acknowledgment
The authors acknowledge the financial assistance from the Indian Council of Medical
Research and TIFAC CORE in NDDS, Government of India, New Delhi, for provid-
ing the research facilities to the team.
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