Biomedical Engineering Reference
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[210] Fennell JP, Brosnan MJ, Frater AJ. Adenovirus-mediated overexpression of extracel-
lular superoxide dismutase improves endothelial dysfunction in a SHR rat model of
hypertension. Gene Ther 2002;9:110-17.
[211] Chu Y, Iida S, Lund DD, Weiss RM, DiBona GF, Watanabe Y, et al. Gene transfer of
extracellular superoxide dismutase reduces arterial pressure in spontaneously hyperten-
sive rats: role of heparin-binding domain. Circ Res 2003;92:461-8.
[212] Goldstein JL, Kita T, Brown MS. Defective lipoprotein receptors and atherosclerosis.
N Engl J Med 1983;309:288-96.
[213] Grossman M, Rader DJ, Muller DMW, Kolansky DM, Kozarsky K, Clark BJ, et al. A
pilot study of ex vivo gene therapy for homozygous familial hypercholesterolaemia. Nat
Med 1995;1:1148-54.
[214] Kozarsky KF, McKinley DR, Austin LL, Raper SE, Stratford-Perricaudet LD, Wilson
JM. In vivo correction of low density lipoprotein receptor deficiency in the Watanabe
heritable hyperlipidaemic rabbit with recombinant adenoviruses. J Biol Chem 1994;269:
13695-703.
[215] Pakkanen TM, Laitinen M, Hippelainen M, Kallionpaa H, Lehtolainen P, Leppanen P,
et al. Enhanced plasma cholesterol lowering effect of retrovirus-mediated LDL receptor
gene transfer to WHHL rabbit liver after improved surgical technique and stimulation of
hepatocyte poliferation by combined partial liver resection and thymidine kinase-ganci-
clovir treatment. Gene Ther 1999;6:34-41.
[216] Kozarsky KF, Jooss K, Donahee M, Strauss JF, Wilson JM. Effective treatment of famil-
ial hypercholesterolaemia in the mouse model using adenovirusmediated transfer of the
VLDL receptor gene. Nat Genet 1996;13:54-62.
[217] Applebaum-Bowden D, Kobayashi J, Kashyap VS, Brown DR, Berard A, Meyn S,
et al. Hepatic lipase gene therapy in hepatic lipase-deficient mice. Adenovirusmediated
replacement of a lipolytic enzyme to the vascular endothelium. J Clin Invest 1996;97:
799-805.
[218] Dugi KA, Vaisman BL, Sakai N, Knapper CL, Meyn SM, Brewer Jr HB, et al.
Adenovirus-mediated expression of hepatic lipase in LCAT transgenic mice. J Lipid
Res 1997;38:1822-32.
[219] Zsigmont E, Kobayashi K, Tzung KW, Li I, Fuke Y, Chan L. Adenovirus-mediated
gene transfer of human lipoprotein lipase ameliorates the hyperlipidemias associated
with apolipoprotein E and LDL receptor deficiencies in mice. Hum Gene Ther 1997;8:
1921-33.
[220] Excoffon KJ, Liu G, Miao L, Wilson JE, McManus BM, Semenkovich CF, et al.
Correction of hypertriglyceridemia and impaired fat tolerance in lipoprotein lipase defi-
cient mice by adenovirus-mediated expression of human lipoprotein lipase. Arterioscler
Thromb Vasc Biol 1997;17:2532-9.
[221] Morishita R, Yamada S, Yamamoto K, Tomita N, Kida I, Sakurabayashi I, et al. Novel
therapeutic strategy for atherosclerosis: ribozyme oligonucleotides against apoli-
poprotein (a) selectively inhibit apolipoprotein (a) but not plasminogen expression.
Circulation 1998;98:1898-904.
[222] Kopfler WP, Willard M, Betz T, Willard JE, Gerard RD, Meidell RS. Adenovirus-medi-
ated transfer of a gene encoding human apolipoprotein A-I into normal mice increases
circulating high-density lipoprotein cholesterol. Circulation 1994;90:1319-27.
[223] Tsukamoto K, Smith P, Glick JM, Rader DJ. Liver-directed gene transfer and prolonged
expression of three major human ApoE isoforms in ApoE-deficient mice. J Clin Invest
1997;100:107-14.
[224] Seppo YH, Martin JF. Cardiovascular gene therapy. Lancet 2000;355:213-22.
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