Gene Delivery Using Chemical Methods - Challenges in Delivery of Therapeutic Genomics and Proteomics - page 205

[396] Veelken H, Mackensen A, Lahn M, Kohler G, Becker D, Franke B, et al. A phase-I
clinical study of autologous tumor cells plus interleukin-2-gene-transfected allogeneic
fibroblasts as a vaccine in patients with cancer. Int J Cancer 1997;70:269-77.
[397] Stopeck AT, Hersh EM, Akporiaye ET, Harris DT, Grogan T, Unger E, et al. Phase I
study of direct gene transfer of an allogeneic histocompatibility antigen, HLA-B7, in
patients with metastatic melanoma. J Clin Oncol 1997;15:341-9.
[398] Stopeck AT, Jones A, Hersh EM, Thompson JA, Finucane DM, Gutheil JC, et al. Phase
II study of direct intralesional gene transfer of allovectin-7, an HLA-B7/beta2-micro-
globulin DNA-liposome complex, in patients with metastatic melanoma. Clin Cancer
Res 2001;7:2285-91.
[399] Meijer SL, Dols A, Urba WJ, Hu H-M, Smith JW, Vetto J, et al. Adaptive cellular
therapy with tumor vaccine draining lymph node lymphocytes after vaccination with
HLA-B7/beta2-microglobulin gene-modified autologous tumor cells. J Immunother
2002;25:359-72.
[400] Zabner J, Cheng SH, Meeker D, Launspach J, Balfour R, Perricone MA, et al.
Comparison of DNA-lipid complexes and DNA alone for gene transfer to cystic fibrosis
airway epithelia in vivo . J Clin Invest 1997;100:1529-37.
[401] Alton EW, Stern M, Farley R, Jaffe A, Chadwick SL, Phillips J, et al. Cationic lipid
mediated CFTR gene transfer to the lungs and nose of patients with cystic fibrosis:
a double-blind placebo controlled trial. Lancet 1999;353:947-54.
[402] Kendrick JE, Matthews KS, Straughn JM, Barnes MN, Fewell J, Anwer K, et al.
A phase I trial of intraperitoneal EGEN-001, a novel IL-12 gene therapeutic, administered
alone or in combination with chemotherapy in patients with recurrent ovarian cancer.
J Clin Oncol 2008;26. abstract 5572.