Information Technology Reference
- Other cardiovascular disease (CVD) risk-related (Boolean) facts (**): target
organ damage (TOD), associated clinical alterations (ACA), diabetes (1).
- Other pathologies suffered by the patient (Boolean) (***): heart failure, post
myocardial infarction, high CVD risk (2), diabetes (1), chronic kidney disease
(3), recurrent stroke prevention.
First Subsystem: CDV Risk Evaluation
The patient's SBP and DBP are used to allocate him in a (refined) category of
BP (Normal/ Prehypertension/ Stage 1 Hypertension/ Stage 2a Hypertension/
Stage 2b Hypertension). This classification is intermediate between those of 
and of [10, 11].
The computational processes involved are simple because the cases are al-
ready separated (disjoint), so they can be translated into IF...THEN... rules,
that can be applied using classifications in simple procedures.
The assessment of the factors in (*) is provided by history, physical exami-
nation, laboratory tests, electrocardiograms...
From the refined BP category obtained and the data in (*), a grade of
CVD risk is calculated using tables [7, 8], that we have also translated into
IF...THEN... rules. The computational processes are simple too (because the
cases are again disjoint). The same will happen with the second subsystem.
Second Subsystem: Hypertension Detection, Evaluation
Now the items in (**) and (***) are assessed: (1) has already been asked in (
(2) has just been evaluated from the data in (*) by the first subsystem; (3) is
deduced from (
) and the information about the rest of the items can be found
in the patient's clinical history.
The patient's SBP and DBP are used to allocate him in a category of BP
(Normal - Prehypertension - Stage 1 Hypertension - Stage 2 Hypertension). This
classification is the one suggested in [10, 11].
From this information, and following a certain treatment algorithm, the au-
thors of [10, 11] recommend:
- individuals who are prehypertensive: practice lifestyle modifications in order
to reduce the risk of developing hypertension (no drug therapy)
- individuals with hypertension (stages 1 and 2) be treated with an appropriate
drug therapy if a first trial of lifestyle modification fails:
individuals with hypertension of stage 1 (not suffering other pathologies)
that need drug therapy be treated with thiazide diuretic (THIAZ) or a
combination including this therapy
individuals with hypertension of stage 2 (not suffering other pathologies)
that need drug therapy be treated with a 2-drug combination
individuals with hypertension of any stage (also suffering from other
pathologies) that need drug therapy should have it adjusted according
to those pathologies.