Chemistry Reference
In-Depth Information
wild type transfer. Most animal cells display rather low sialylation level
but CHO cells express a ST3Gal transferase although they lack the ST6Gal
enzyme and observe that these variants could add sialic acid on bi-, tri-
and tetraantennary glycans. Preliminary data further show that hCG is a
good acceptor for them, thereby demonstrating for the first time that
gonadotropins can be glyco-optimized in their outer glycosylation to
produce long-lasting analogs similar to the most active glycoforms
known for gonadotropins.
References
1 B. Lunenfeld, Human Reprod. Update, 2004, 10, 453.
2 N. S. Macklon, R. L. Stouffer, L. C. Giudice and B. C. J. M. Fauser, Endocrine
Rev., 2006, 27, 170.
3 L. A. Cole, Reprod. Biol. Endocrinol., 2010, 8, 102.
4 S. Berndt, S. Blacher, C. Munaut, J. Detilleux, S. Perrier d'Hauterive,
I. Huhtaniemi, D. Evain-Brion, A. No¨l, T. Fournier and J. M. Foidart, FASEB
J, 2013, 27, 1309.
5 H. F. Acevedo and R. J. Hartsock, Cancer, 1996, 78, 2388.
6 D. Li, X. Wen, L. Ghali, F. M. Al-Shalabi, S. M. Docherty, P. Purkis and R. K.
Iles, Histopathology, 2008, 53, 147.
7 R. K. Iles, Mol. Cell.Endocrinol., 2007, 260-262, 264.
8 S. A. Butler and R. K. Iles, Clin. Cancer Res., 2003, 9, 4666.
9 W. D. Odell and J. Grin, N. Engl. J. Med., 1987, 317, 1688.
10 W. D. Odell and J. Grin, J. Clin.Endocrinol.Metab., 1989, 69, 528.
11 P. F. Policastro, S. Daniels-McQueen, G. Carlell and I. Boime, J. Biol. Chem.,
1986, 261, 5907.
12 C. Hagen, K. P. McNatty and A. S. McNeilly, J. Endocrinol., 1976, 69, 33.
13 E. Moy, L. M. Kimzey, L. M. Nelson and D. L. Blithe, Endocrinology, 1996,
137, 1332.
14 Y. Ashitaka, R. Nishimura, K. Futamura, M. Oashi and S. Tojo, Endocrinol.
Jpn., 1974, 21, 547.
15 M. B´geot, F. J. Hemming, P. M. Dubois, Y. Combarnous, M. P. Dubois and
M. L. Aubert, Science, 1984, 226, 566.
16 D. L. Blithe, R. G. Richards and M. C. Skarulis, Endocrinology, 1991, 129,
2257.
17 E. A. Stewart, M. S. Rein, A. J. Friedman, L. Zuchowski and R. A. Nowak, Am.
J. Obstet. Gynecol., 1994, 170, 677.
18 M. Roger, N. Lahlou, B. Couzinet, J. L. Chaussain and R. Scholler, J. Steroid.
Biochem, 1989, 33, 763.
19 K. M. Fox, J. A. Dias and P. van Roey, Mol. Endocrinol., 2001, 15, 378.
20 Q. R. Fan and W. A. Hendrickson, Nature, 2005, 433, 269.
21 X. Jiang, H. Liu, X. Chen, P. Chen, D. Fischer, V. Sriraman, H. N. Yu,
S. Arkinstall and X. He, Proc. Natl. Acad. Sci. U.S.A., 2012, 109, 12491.
22 A. J. Lapthorn, D. C. Harris, A. Littlejohn, J. W. Lustbader, R. E. Canfield,
K. J. Machin, F. J. Morgan and N. W. Isaacs, Nature, 1994, 369, 455.
23 M. Tegoni, S. Spinelli, M. Verhoeyen, P. Davis and C. Cambillau, J. Mol.
Biol., 1999, 289, 1375.
24 E. Alvarez, C. Cahoreau and Y. Combarnous, Reprod. Biol. Endocrinol., 2009,
7, 90.
25 A. Amoresano, R. Siciliano, S. Orru, R. Napoleoni, V. Altarocca, E. De Luca,
A. Sirna and A. Pucci, Eur. J. Biochem., 1996, 242, 608.
Search WWH ::
Custom Search