MRI Measurement of Heart Wall Motion - Advance Image Processing in Magnetic Resonance Imaging - page 357

same technique. Both HARP and DENSE are methods designed to select one
spectral peak of the SPAMM-tagged signal. In HARP, the peak is selected using
a software filter and can be shifted to the center of k-space to give an image
whose phase is proportional to displacement. In DENSE, the spectral peak is
selected using hardware filters (i.e., by manipulating the signal acquired by the
scanner) and is shifted to the center of k-space using the decoding gradient.
Because a k-space filter is not required for DENSE, the resolution of the dis-
placement map is greater. This increased spatial resolution comes at the cost of
reduced SNR and intravoxel dephasing at high strains or rotations.

REFERENCES

1. Herman, M.V., Heinle, R.A., and Klein, M.D., (1967). Localized disorders in

myocardial contraction: Asynergy and its role in congestive heart failure. New
Eng. J. Med. 277: 222-232.

2. Hunter, P.J. and Smaill, B.H. (1988). The analysis of cardiac function: a continuum

approach. Prog. Biophys. Mol. Biol. 52: 101-164.

3. http://www.bioeng.auckland.ac.nz/physiome/physiome.php (accessed July 30,

2004).

4. Rodriguez, F., Tibayan, F.A., Glasson, J.R., Liang, D., Daughters, G.T., Ingels,

N.B., Jr., and Miller, D.C. (2004). Fixed-apex mitral annular descent correlates
better with left ventricular systolic function than does free-apex left ventricular
long-axis shortening. J. Am. Soc. Echocardiogr. 17(2): 101-107.

5. Feng, Q., Song, W., Lu, X., Hamilton, J.A., Lei, M., Peng, T., and Yee, S.P. (2002).

Development of heart failure and congenital septal defects in mice lacking endot-
helial nitric oxide synthase. Circulation 106(7): 873-879.

6. Young, A.A. (1991). Epicardial deformation from coronary cineangiograms. in

Glass, L., Hunter, P.J., McCulloch, A.D., (Eds.). Theory of Heart , Springer-Verlag,
pp. 175-208.

7. Miyatake, K., Yamagishi, M., Tanaka, N., Uematsu, M., Yamazaki, N., Mine, Y.,

Sano, A., and Hirama, M. (1995) New method for evaluating left ventricular wall
motion by color-coded tissue Doppler imaging: in vitro and in vivo studies.
J. Am. Coll. Cardiol. 25: 717-724.

8. D'Hooge, J., Heimdal, A., Jamal, F., Kukulski, T., Bijnens, B., Rademakers, F.,

Hatle, L., Suetens, P., and Sutherland, G.R. (2000). Regional strain and strain rate
measurements by cardiac ultrasound: principles, implementation and limitations.
Eur. J. Echocardiogr. 1: 154-170.

9. Amini, A.A. and Prince, J.L. (2001). Measurement of Cardiac Deformations from

MRI: Physical and Mathematical Models. Dordrecht: Kluwer Academic Publishers.

10. Morse, O.C. and Singer, J.R. (1970). Blood velocity measurement in intact sub-

jects. Science 170: 440-441.

11. Axel, L., Shimakawa, A., and MacFall, J. (1986). A time-of-flight method of

measuring flow velocity by magnetic resonance imaging. Magn. Res. Imaging
4(3): 199-205.

12. Zerhouni, E.A., Parish, D.M., Rogers, W.J., Yang, A., and Shapiro, E.P. (1988).

Human heart: tagging with MR imaging — a method for noninvasive assessment
of myocardial motion. Radiology . 169(1): 59-63.