Mechanisms Underlying the Initiation and Dynamics of Neuronal Filopodia: From Neurite Formation to Synaptogenesis - International Review of Cell and Molecular Biology - page 113

Figure 3.3 Subfilopodial compartmentalization. (A) Schematic showing the general
subfilopodial localization of a variety of proteins found in filopodia. The filopodium is
divided into three components: base, shaft and tip. The shaft is further divided into a
proximal segment and the rest of the more distal shaft. References are provided in the
text. (B) Example of antidrebrin staining in a filopodium counterstained with phalloidin
to reveal actin filaments. Note that drebrin is largely confined to the proximal part of the
shaft. The arrowhead denotes the distal extent of drebrin localization along the shaft.
(C) Distribution of myosin IIA and IIB in a triple labeled filopodium. Puncta of both myo-
sins are found throughout the filopodium. For color version of this figure, the reader is
referred to the online version of this topic.