Biomedical Engineering Reference
In-Depth Information
formulations in three-dimensional patterns. Both chemically and physically
crosslinked elastic hydrogels can be rendered biodegradable through the introduc-
tion of hydrolytically sensitive groups into the networks. Due to their biocompat-
ibility, biodegradability, and good mechanical properties, biodegradable elastic
hydrogels are good candidates as biomaterials for use in medical applications,
including tissue engineering. These hydrogels have been used as biodegradable
sutures and scaffold materials to engineer various types of tissues in mechanical
dynamic environments. Elastic hydrogels with described properties are promising
expander candidates which may contribute to more effective harvesting of tissue
for reconstructive interventions. However, the synthesis of biodegradable hydro-
gels with rubberlike elasticity and strength is not easy. Moreover,
in vivo
tests
should be done to improve the clinical applicability of elastic hydrogels for tissue
expansion as well as other medical applications.
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