Microfluidics - Introduction to BioMEMS - page 133

(a)

PDMS replica

Plastic substrate

OH OH OH OH

OH OH OH OH OH OH OH OH OH

OH OH OH OH OH

3-aminopropyl
triethoxysilane
(APTES)

3-glycidoxypropyl
triethoxysilane
(GPTES)

(b)

Plastic substrate

PDMS replica

OOO
Si

OOO
Si

OOO
Si

OOO
Si

OOO OOO OOO OOO OOO

OOO OOO

Si

OOO
Si

Si Si Si Si Si

Si

NH 2 NH 2 NH 2 NH 2 O O O O O

NH 2 NH 2 NH 2

O O O O O

25°C, 1 h

(c)

OOO
Si

PDMS replica

APTES
GPTES

Plastic substrate

Si

OOO

FIGURE 3.20 Room. temperature. bonding. of. PDMS. to. plastics. using. silanes.. (From. Linzhi. Tang.
and.Nae.Yoon.Lee,.“A.facile.route.for.irreversible.bonding.of.plastic-PDMS.hybrid.microdevices.at.
room.temperature,”. Lab Chip 10,.1274-1280,.2010..Reproduced.with.permission.from.The.Royal.
Society.of.Chemistry.)

Assemble

FIGURE 3.21 Modular. microluidics.. (From. Minsoung. Rhee. and. Mark. A.. Burns,. “Microluidic.
assembly.blocks,”. Lab Chip .8,.1365-1373,.2008..Reproduced.with.permission.from.The.Royal.
Society.of.Chemistry.)