Biomedical Engineering Reference
In-Depth Information
0
60
120
600
150 µm
FIGURE 2.50
Electroactive. release. of. cells. from. micropatterns.. Numbers. indicate. minutes. elapsed.
after.application.of.the.voltage.pulse..(From.Xingyu.Jiang,.Rosaria.Ferrigno,.Milan.Mrksich,.and.George.
M..Whitesides,.“Electrochemical.desorption.of.self-assembled.monolayers.noninvasively.releases.pat-
terned.cells.from.geometrical.coninements,”.
J. Am. Chem. Soc.
.125,.2366-2367,.2003..Reprinted.
with.permission.of.the.American.Chemical.Society..Figure.contributed.by.George.Whitesides.)
hυ
Photo
deprotection
1. EChem oxidation
2. Ligand immobilization
Cell
culture
100
Г (a.u.)
0
0
80
D (a.u.)
FIGURE 2.51
Dynamic.surface.gradients.using.electroactive.SAMs..(From.E..W..L..Chan,.S..Park,.
and.M..N..Yousaf,.“An.electroactive.catalytic.dynamic.substrate.that.immobilizes.and.releases.pat-
terned.ligands,.proteins,.and.cells,”.
Angew. Chem. Int. Ed.
47
,
6267-6271,.2008..Figure.contrib-
uted.by.Muhammad.Yousaf.)
