Body contouring: Noninvasive fat reduction - Lasers and Energy Devices for the Skin - page 291

Table 12.1 Devices and Treatments for the Selective Targeting of Fat Tissue

Time per
Treatment
per Site

Mechanism of
Adipocyte Damage

Anesthesia and
Analgesia

Time to Results
(Reported)

Clearance
Status

Treatment Brand Names Indications Areas Treated

Cryolipolysis Zeltiq Cold-induced

apoptosis

Focal adiposity Flanks and

abdomen

None 60 min 3 mo FDA cleared

TFU LipoSonix Thermal

destruction

Focal adiposity and
skin tightening

Abdomen, fl anks,
and buttocks

Oral analgesics 90 min 90 d FDA approved

NTFU UltraShape Cavitation reduction Focal adiposity Abdomen None 30-90 min 3-4 wk FDA clearance

pending

Low-level laser
therapy

Various Nonthermal defl ation

(in vitro)

Focal adiposity and
skin tightening

Abdomen, thighs,
fl anks, and neck

None 20-30 min 2-4 wk FDA cleared

Infrared laser Photothermolysis Focal adiposity Abdomen Topical or

injected
anesthesia

~10 min 4-6 wk Not FDA cleared

Radiofrequency Thermage

Exilis
Endymed

Thermal reduction Focal adiposity and

skin tightening

Abdomen,
thighs, buttocks,
extremities,
and face

None ~30 min to

2 hr

4-12 wk FDA cleared

Abbreviations : d, day; mo, month; NTFU, nonthermal focused ultrasound; TFU, thermal focused ultrasound; wk, week.