Biomedical Engineering Reference
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Figure 10.16 Complexion analysis of the right cheek of a white male ( A ) before and ( B ) after one aminolevulinic acid-photodynamic therapy session for
photorejuvenation. A 47% decrease in brown spots (solar lentigines) was quantifi ed using the computer software system.
( A )
( B )
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Figure 10.17 ( A ) Frontal view of a 51-year-old male with photodamage consisting of numerous solar lentigines. ( B ) One day after ALA-PDT treatment. Levulan
ALA was applied to the entire treatment area for 1 hour, unoccluded. IPL treatment with Lumenis One using a 560 nm cutoff fi lter, double pulse of 4 and 4 ms
with a 10 ms delay at a fl uence of 18 J/cm 2 followed by a 10-minute exposure with the Blu-U. Note the erythema and crusting of all actinically damaged skin.
( C ) Two days after PDT, treatment, further increase in erythema is seen in areas of actinically damaged skin. ( D ) Three days after PDT treatment, resolution of ery-
thema begins. ( E ) Four days after PDT treatment, further resolution of erythema. ( F ) Seven days after PDT treatment, complete resolution of erythema.
Abbreviations : ALA, aminolevulinic acid; IPL, intense pulsed light; PDT, photodynamic therapy. Source : From Ref. 64.
 
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