Biomedical Engineering Reference
In-Depth Information
allowed the development of optics that drive energy more deeply
and more safely to obtain better results on scars and other clini-
cal problems. NAFL's proven effi cacy in a multitude of skin con-
ditions leads us to utilize NAFL as an integral part of our daily
practice of dermatology and medicine. Clinical applications
include among others photodamage, wrinkling, acne and surgi-
cal scars, stretch marks, pigmentary disorders, and actinic kera-
tosis. Study after study demonstrates that fractional resurfacing
is effective, safe, and has minimal side effects. NAFL continues to
be further refi ned and ongoing studies will elucidate better set-
tings and newer applications. Enhancement of penetration of
topicals including levulinic acid for photodynamic therapy is
among the many uses currently being developed.
21. Alster TS, Wanitphakdeedecha R. Improvement of post-fractional laser
erythema with light-emitting diode photomodulation. Dermatol Surg
2009; 35: 813-15.
22. Fisher GH, Geronemus RG. Short-term side effects of photothermolysis.
Dermatol Surg 2005; 31: 1245-9.
23. Firoz B, Katz T, Goldberg L, et al. Herpes zoster in the distribution of the
trigeminal nerve after nonablative fractional photothermolysis of the
face: report of 3 cases. Dermatol Surg 2011; 37: 249-52.
24. Metelitsa AI, Alster TS. Fractionated laser skin resurfacing treatment
complications: a review. Dermatol Surg 2010; 36: 299-306.
25. Vaiyavatjamai P, Wattanakrai P. Side effects and complications of
fractional 1550-nm erbium fi ber laser treatment among Asians. J Cosmet
Dermatol 2011; 10: 313-16.
26. Graber EM, Tanzi EL, Alster TS. Side effects and complications of
fractional laser thermolysis: experience with 961 treatments. Dermatol
Surg 2008; 34: 305-7.
27. Tierney EP, Kouba DJ, Hanke CW. Review of fractional photothermolysis:
treatment indications and effi cacy. Dermatol Surg 2009; 35: 1445-61.
28. Alexiades-Armenakas MR, Dover JS, Arndt KA. The spectrum of laser
skin resurfacing: nonablative, fractional and ablative laser resurfacing. J
Am Acad Dermatol 2008; 58: 719-37.
29. Blankenship CM, Alster TS. Fractional photothermolysis of residual
hemangioma. Dermatol Surg 2008; 34: 1112-14.
30. Izikson L, Anderson RR. Resolution of blue minocycline pigmentation of the
face after fractional photothermolysis. Lasers Surg Med 2008; 40: 399-401.
31. Liu A, Hexsel CL, Moy RL, et al. Granuloma annulare successfully treated
using fractional photothermolysis with a 1550-nm erbium doped yttrium
aluminum garnet fractionated laser. Dermatol Surg 2011; 37: 712.
32. Kouba DJ, Fincher EF, Moy RL. Nevus of Ota successfully treated by
fractional photothermolysis using a fractionated 1,440 nm ND:YAG laser.
Arch Dermatol 2008; 144: 156-8.
33. Wanner M, Tanzi EL, Alster TS. Fractional photothermolysis: treatment
of facial and nonfacial cutaneous photodamage with a 1,550-nm erbium-
doped fi ber laser. Dermatol Surg 2007; 33: 23-8.
34. Jih MH, Goldberg LH, Kimyai-Asadi A. Fractional photothermolysis for
photoaging of hands. Dermatol Surg 2008; 34: 73-8.
35. Vasily DB, Cerino ME, Ziselman EM, et al. Non-ablative fractional
resurfacing of surgical and post-traumatic scars. J Drugs Dermatol 2009;
11: 998-1005.
36. Tierney E, Mahmoud BH, Srivastava D, et al. Treatment of surgical scars
with nonablative fractional laser versus pulsed dye laser: a randomized
controlled trial. Dermatol Surg 2009; 35: 1172-80.
37. Haedersdal M, Moreau KE, Beyer DM, et al. Fractional nonablative 15450
nm resurfacing for thermal burn scars: a randomized controlled trial.
Lasers Surg Med 2009; 41: 189-95.
38. Niwa AB, Mello AP, Torezan LA, et al. Fractional photothermolysis for the
treatment of hypertrophic scar: clinical experience of eight cases.
Dermatol Surg 2009; 35: 773-7.
39. Glaich AS, Rahman Z, Goldberg LH, et al. Fractional resurfacing for the
treatment of hypopigmented scars: a pilot study. Dermatol Surg 2007; 33:
289-94.
40. Weiss RA, Weiss MA, Beasley KL. Long term experience with fi xed array
1540 fractional erbium laser for acne scars. Lasers Surg Med 2008; 68: 27.
41. Alster TS, Tanzi EL, Lazarus M. The use of fractional laser photothermolysis
for the treatment of atrophic scars. Dermatol Surg 2007; 33: 295-9.
42. Elsaie ML, Baumann LS, Elsaaiee LT. Striae distensae (stretch marks) and
different modalities of therapy: an update. Dermatol Surg 2009; 35: 563-73.
43. De Angelis F, Kolesnikova L, Renato F, et al. Fractional nonablative 1540-nm
laser treatment of striae distensae in Fitzpatrick skin types II-IV: clinical and
histological results. Aesthet Surg J 2011; 31: 411-19.
44. Stotland M, Chapas AM, Brightman L, et al. The safety and effi cacy of
fractional photothermolysis for the correction of striae distensae. J Drugs
Dermatol 2008; 7: 857-61.
45. Sheth VM, Pandya AG. Melasma: a comprehensive update, part I. J Am
Acad Dermatol 2011; 65: 689-97.
46. Tierney EP, Hanke CW. Review of the literature: treatment of
dyspigmentation with fractionated resurfacing. Dermatol Surg 2010; 36:
1499-508.
47. Sheth VM, Pandya AG. Melasma: a comprehensive update, part II. J Am
Acad Dermatol 2011; 65: 699-714.
48. Rokhsar CK, Fitzpatrick RE. The treatment of melisma with fractional
photothermolysis: a pilot study. Dermatol Surg 2005; 31: 1645-50.
references
1. Manstein D, Herron G, Sink RK, et al. Fractional photothermolysis: a new
concept for cutaneous remodeling using microscopic patterns of thermal
injury. Lasers Surg Med 2004; 34: 426-38.
2. Bernstein L, Kauvar A, Grossman M, et al. The short and long term side
effects of carbon dioxide laser resurfacing. Dermatol Surg 1997; 23:
519-25.
3. Helm T, Shatkin S Jr. Alabaster skin after CO 2 laser resurfacing: evidence
for suppressed melanogenesis rather than just melanocytic destruction.
Cutis 2006; 77: 15-17.
4. Bhatia A, Dover J, Arndt K, et al. Patient satisfaction and reported long-
term therapeutic effi cacy associated with 1,320 nm Nd:YAG laser treatment
of acne scarring and photoaging. Dermatol Surg 2006; 32: 346-52.
5. Tanzi E, Alster T. Comparison of a 1450 nm diode laser and a 1320 nm
Nd:YAG laser in the treatment of atrophic facial scars: a prospective
clinical and histological study. Dermatol Surg 2004; 30: 152-7.
6. Lupton J, Williams C, Alster T. Non-ablative laser skin resurfacing using a
1540 nm erbium glass laser: A clinical and histologic analysis. Dermatol
Surg 2002; 28: 833-5.
7. Chan H, Lam L, Wond D, et al. Use of 1,320 nm laser for wrinkle reduction
and the treatment of acne scarring in Asians. Lasers Surg Med 2004; 34:
98-103.
8. Hantash B, Bedi V, Sudireddy V, et al. Laser-induced transepidermal
elimination of dermal content by fractional photothermolysis. J Biomed
Opt 2006; 11: 041115.
9. Laubach H, Tannous Z, Anderson R, et al. Skin responses to fractional
photothermolysis. Lasers Surg Med 2006; 38: 142-9.
10. Data on fi le, Solta Medical, Hayward, CA. [Available from: http://www
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11. Data on fi le, Palomar Medical Technologies, Inc., Burlington, MA.
[Available from: http://www.palomarmedical.com/resources.aspx]
12. Data on fi le, Cynosure Inc., Westford, MA. [Available from: http://www
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13. Peterson JD, Goldman MP. Rejuvenation of the aging chest: a review and
our experience. Dermatol Surg 2011; 37: 555-71.
14. Jang WS, Lee CK, Kim BJ, et al. Effi cacy of 694 nm Q-switched ruby
fractional laser treatment of melasma in female Korean patients. Dermatol
Surg 2011; 37: 1133-40.
15. Lee GY, Lee HI, Kim WS. The effect of a 1550 nm fractional erbium - glass
laser in female pattern hair loss. J Eur Acad Venerol 2011; 25: 1450-4.
16. Kim WS, Lee HI, Lee JW, et al. Fractional photothermolysis laser treatment
of male pattern hair loss. Dermatol Surg 2011; 37: 41-51.
17. Shin MK, Lee JH, Lee SJ, Kim NI. Platelet-rich plasma combined with
fractional laser therapy for skin rejuvenation. Dermatol Surg 2012. doi:
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18. Marra DE, Yip D, Fincher EF, et al. Systemic toxicity from topically applied
lidocaine in conjunction with fractional photothermolysis. Arch
Dermatol 2006; 142: 1024.
19. Sherling M, Friedman PM, Adrian R, et al. Consensus recommendations
on the use of an erbium-doped 1,550-nm fractional laser and its
applications in dermatologic laser surgery. Dermatol Surg 2010; 36: 461-9.
20. Fisher GH, Kim KH, Bernstein LJ, et al. Concurrent use of a handheld
forced cold air device minimizes patient discomfort during fractional
photothermolysis. Dermatol Surg 2005; 31: 1242-3.
 
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