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Figure 2. Anna Ursyn, “Micro Macro” (© 2008, A. Ursyn. Used with permission)
formation and evolution of the synthetic virtual
plasmodium based on a single-cell organism
Phy-
sarum polycephalum
serves as a virtual computing
material for designing distributed unconventional
computing devices (Jones, 2011). Adamatzky, De
Lacy Costello, Holley, Gorecki, & Bull (2011)
imitated arrangements of vesicles as Voronoi au-
tomata - finite state machines defined on a planar
Voronoi diagram. According to Wolfram (2012), a
particularly notable use of a Voronoi diagram was
the analysis of the 1854 cholera epidemic in London,
in which physician John Snow determined a strong
correlation of deaths with proximity to a particular
(and infected) water pump on Broad Street).
Voronoi diagrams are applied in many fields
of science and engineering. Voronoi diagram is
generated from Voronoi polygons where each
polygon contains exactly one generating point
and every point in a given polygon is closer to
its generating point than to any other (Wolfram,
2012). Andrew Adamatzky (2010) experimentally
demonstrated that plasmodium
Physarum poly-
cephalum
approximates a planar Voronoi diagram,
and then developed a Physarum construction from
Voronoi diagram. One can see how such diagrams
are formed on stones colonized by lichens. A Phy-
sarum machine is a biological computing device, a
programmable biological computer implemented
