Overview of the Manifold VNPs Used in Nanotechnology - Viral Nanoparticles: Tools for Materials Science and Biomedicine - page 38

.. Sulfolobus islandicus rod-Shaped Virus : An Archaeal
Virus

SIRV2 is an archaeal virus from the family, which is a group of non-

enveloped, rod-shaped viruses with linear double-stranded DNA genomes
(Prangishvili

Rudiviridae

., 2006). SIRV2 infects strains of the gases and steam), hot,
acidic spring in Iceland with temperature 88

et al

C and pH 2.5. SIRV2 grows in
a truly extreme environment. Due to its hyperthermophilic archaeal genus

°

Figure 2.13 Structure of SIRV2 particles. (A). TEM of negatively stained SIRV2 particles.

Inset shows a high-resolution image of the end structure of the capsid. The scale bar
is 500 nm. (B). Schematic depiction of SIRV2 particles. Reproduced with permission
from Steinmetz, N. F., Bize, A., Findlay, K. C., Lomonossoff, G. P., Manchester, M., Evans,
D. J., and Prangishvili, D. (2008) Site-specific and spatially controlled addressability of
a new viral nanobuilding block: Sulfolobus islandicus rod-shaped virus 2, Adv . Funct .

Mater ., 18 , 3478-3486.