Biomedical Engineering Reference
In-Depth Information
FIGURE 13.5
An example of intersubject registration: an atlas of the brain is constructed by averaging
the MR images of seven normal subjects (top row) after rigid registration, (middle
row) after affine registration, and (bottom row) after nonrigid registration using free form
deformations.
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align the images. The bottom row shows the atlas obtained by using a non-
rigid transformation based on freeform deformations.
Another important area of application which requires the matching of
computerized atlantes is the automated segmentation and labeling of com-
plex structures of the brain.
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Many of these approaches are based on the
understanding that only the use of statistical models of shape and intensity
enables automatic identification of complex structures such as the human brain.
