Biomedical Engineering Reference
In-Depth Information
9
Registration of MRI and PET Images
for Clinical
Applications
Uwe Pietrzyk*
CONTENTS
9.1 Introduction ................................................................................................ 199
9.2 Properties of PET Images .......................................................................... 200
9.3 Properties of Magnetic Resonance Images ............................................. 203
9.4 Problems and Solutions in MRI-PET Registration ................................ 204
9.4.1 General Considerations for Accurate Registration
of MR and PET Images.................................................................. 204
9.4.2 Techniques and Procedures used in Clinical Applications ...... 207
9.5 Discussion of Applications in a Clinical Setting.................................... 209
9.5.1 Introductory Remarks; Definitions.............................................. 209
9.5.2 Registration of PET and MR Images of the Brain...................... 210
9.5.3 Registration of Extracranial PET and MR Images..................... 210
9.6 Conclusions................................................................................................. 213
Acknowledgments .............................................................................................. 214
References ............................................................................................. 215
9.1
Introduction
Positron emission tomography (PET) and magnetic resonance imaging (MRI)
are prominent examples of functional and morphological imaging modalities,
respectively. The imaging concepts of PET and MRI are quite different, as are the
images. MRI and PET are useful in conjunction precisely because they are com-
plementary. While PET is able to provide information about a specific function
* Part of this work was done while the author was at the Max-Planck Institute of Neurological
Research, Cologne, Germany.
