Biology Reference
In-Depth Information
Fig. 4.
Inner tegument proteins of HSV-1 and HCMV. (
a
) CryoEM
reconstruction of HSV-1 virion showing the inner tegument proteins in
color. (
b
) CryoEM reconstruction of HCMV virion showing inner tegument
proteins in purple. (
c
) Close-up view of a computationally extracted portion
of the HSV-1 virion reconstruction. The tegument densities, colored in yel-
low, make contact with the upper domains of the penton and its adjacent
triplexes, but not the upper domains of any hexons. (
d
) Close-up view of a
computationally isolated portion of the HCMV virion reconstruction. The
tegument densities interact with the upper domains of all pentons, hexons,
and triplexes by attaching one end to the upper domain of a hexon (or pen-
ton) and anchoring the other end on the upper domain of the adjacent
triplex. Color codes in (
c
) and (
d
): red, penton; blue, hexon; green, triplex;
yellow, tegument density.
