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Table 3. Predicted Probability of Yields in the Presence of Various Ratios of Mutant and Wild-type Components when
Z varies from 1 to 6 and X
=
1*.
Φ
Probability of
29 Assembly with:
Mutant RNA
( P ) (%)
=
=
=
=
=
=
=
=
=
=
=
=
Z
6, X
0
Z
5, X
1
Z
4, X
1
Z
3, X
1
Z
2, X
1
Z
1, X
1
0
1
0
1
1
1
0
10
0.533333
0.600000
0.666667
0.733333
0.800000
0.9
20
0.263333
0.326667
0.400000
0.500000
0.633333
0.8
30
0.116667
0.166667
0.240000
0.333333
0.500000
0.7
40
0.046667
0.076667
0.130000
0.216667
0.366667
0.06
50
0.015667
0.031000
0.063333
0.125000
0.250000
0.5
60
0.004000
0.010000
0.027000
0.063333
0.160000
0.4
70
0.000730
0.002433
0.008000
0.027000
0.090000
0.3
80
0.000063
0.000320
0.001600
0.008000
0.040000
0.2
90
0.000001
0.000010
0.000100
0.001000
0.010000
0.1
100
0
0
0
0
0
0
* Predications were make for conditions where the number of pRNAs pre procapsid that were required for packing ( Z ) was varied
from 1 to 6, while the number of mutant pRNAs pre procapsid that were sufficient to inhabit packing ( X ) was predicted to be 1.
(Adapted from Ref. 107, with permission from the author and the publisher, American Society for Microbiology.)
 
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