HETEROGENEOUS NANOSTRUCTURES FOR BIOMEDICAL DIAGNOSTICS - Bio-Inspired and Nanoscale Integrated Computing - page 440

OxLDL attaching to
antibody

NH 2
NH 2

NH 2

NH 2

OOC

−

COO −

− OOC

COO

−

NH 2

PEI PEG

OH

N

HO

N

H

n

X

Y

Figure 16.11. The nanosensor was coated with a layer of PEI/PEG polymer, followed
by the attachment of antibodies to the primary amine of PEI. This sensor was then
exposed to various biospecies, including oxLDL and oxidized cytochrome C. Selectivity
is achieved via the selective binding of oxLDL to the antibodies.

investigate the mechanisms by which the characteristics of shear stress regulates
the biological activities of endothelial cells at the complicated arterial geometry.
MEMS shear stress sensors are operated based on the heat transfer principle
[37] by which the voltage output of the MEMS sensors is responsive to the