Biomedical Engineering Reference
In-Depth Information
7.4
Summary
So far, we have discussed the use of various physical means to stimulate bone cells
for the regeneration of bone tissues. These include exploiting use of optics (optical
tweezers), magnetism (magnetic twisting and pulling), and forces (nanoindenta-
tion). Further development on using other methods of stimulation is also likely to
emerge.
The major obstacles that the existing methods face are not their precision but the
complexity of the mechanical forces our bone experiences everyday. To simulate
these forces, a very complex model is needed and one single stimulation method
may not be enough.
The formation of bone tissue
in vitro
has already been proved to be successful
[66]. To use these engineered bone tissues in repairing damages may be far from
straightforward. We need to consider the compatibility of the implant in terms
of mechanical strength. This is particularly tricky when we have to consider the
interface between the original tissue and the implant. Quite often, such a defect
becomes the point of weakness. Nonetheless, the pace of progress in this research
area is an encouraging sign that such repairing technique will soon be available to
the public.
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