Biomedical Engineering Reference
In-Depth Information
Fig. 2 Non-contact spotting. Free fly of droplets allow very small CVs in the amounts deposited
onto a surface. The printing process has very low CVs and with repetition rates of up to 1000 Hz
is potentially very fast which is shown in fig.
3
Fig. 3
Determination of droplet volumes using piezo driven non-contact dispensers
One immediate drawback of non-contact spotting procedures becomes obvious
when the z-movement of the spotting head has to be minimized to allow for fast
production: electrostatic charge as present in most polymer plates creates a field
which influences the trajectory of a deposited protein-containing droplet. The
resulting array will show spots that have all an identical size, but will be placed in
